Q. In 1839, Matthias Schleiden and Theodor Schwann discovered that trypsin could be used for degradation of matrix proteins.

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Q. The development of __________ formed the basis of modern tissue engineering.

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Q. When was Tissue engineering conceptualized?

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Q. When was the first neuronal tissue culture line developed?

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Q. Karl Thiersch was a german surgeon in Munich. He attempted to grow skin cells into granulation wounds. While doing so, he discovered the importance of granulation tissue in the process of wound healing in 1874. In which stage of wound healing does granulation occur?

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Q. Ross Harrison was the first one to develop a neuronal cell line in the year 1912. This was followed by the development of stem cell lines by Alexis Carrel.

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Q. Who invented the technique of cell culture?

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Q. Thin split thickness skin grafts were first introduced in 1872 by ______ in France, and later by ______ in Germany in 1874.

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Q. When was the term “Tissue engineering” coined?

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Q. What is the Goal of Tissue Engineering?

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Q. The driving force behind the conceptualization of in vivo culturing of tissues was the limited number of donors available and graft-rejection by the immune system.

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Q. Prosthetic devices are capable of restoring normal function, and the number of organ donors is always way less than required.

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Q. Which is the Competent Authority for tissues and cells in the United Kingdom?

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Q. Title ______________ constitutes of a comprehensive regulatory Framework for the producers of human cells, tissues, and cellular and tissue-based products (HCT/Ps).

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Q. Which Act governs the manufacture of HCT/Ps?

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Q. Umbilical cord blood stem cells are an example of 361 HCT/Ps that meet the criteria in Title 21 of CFR part 1271.

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Q. _____________ need to register with FDA under Title 21 of Code of Federal Regulations (CFR).

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Q. Name one 361 HCT/P which cannot be imported.

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Q. Which of the following Tissue Engineering products has been approved by the European Medicines Agency (EMA) as an Advanced Therapy medicinal product (Drug)?

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Q. What is the main component of the tissues in our body?

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