Question

Which one is the rate-limiting step in the oxidation of xenobiotics?

a.

Binding of the substrate to Fe³⁺

b.

Electron transfer from NADPH to the above complex

c.

The enzyme-substrate complex combines with a molecule of oxygen forming a ternary complex

d.

Ternary complex gains an electron from the NADPH

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Answer: (b).Electron transfer from NADPH to the above complex

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Q. Which one is the rate-limiting step in the oxidation of xenobiotics?
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