Q. Topoisomerases I and II differ only on the number of steps required to change the linking number.

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Q. Which special enzyme introduces negative supercoils in DNA?

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Q. Which of the following is not a property of topoisomerase?

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Q. Topoisomerases introduces catenation to promote cell division.

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Q. Type I topoisomerase can never decatenate catenated circular DNA?

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Q. The promotion of DNA breaking and rejoining by topoisomerase requires______________

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Q. Attack of the topoisomerase gives rise to ____________

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Q. To reseal the DNA backbone where does topoisomerase gets the energy from?

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Q. Which of the following does not occur during cell division in prokaryotes?

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Q. The active site of the topoisomerase contains a tyrosine residue.

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Q. Nucleosome was first described in 1974 by ___________

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Q. The extent of chromosome coiling in non – dividing cells is _________

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Q. The whole length of DNA is transcriptionally active.

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Q. Why are chromosomes condensed?

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Q. At which phase do transcription ceases?

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Q. The part that plays a critical role in even distribution of parental DNA during division is ___________

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Q. With respect to centromere which of the following is wrong?

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Q. The protein that binds to the spindle fibres are known as centromeric proteins.

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Q. Centromeric DNA was initially defined in ___________

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Q. How many satellite sequence elements are present in yeast centromere?

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