Q. The functional product of the Xist gene is ___________

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Q. All genes on the inactivated X chromosome are transcriptionally silent.

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Q. The X-chromosome once inactivated remains inactive throughout the life in all the cells of the body.

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Q. What changes occur in the chromosome to make it inactive?

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Q. Barr body is the ___________

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Q. The best genetic mosaicism is observed in which of the following?

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Q. Female mammals are called genetic mosaics.

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Q. The maternal X-chromosome is inactivated during Dosage compensation.

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Q. The proposal for the concept of X-chromosome inactivation in female XX-chromosomes was experimentally shown in ___________

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Q. X-chromosome inactivation is known as ______________

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Q. `11

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Q. The phenomenon of allelic exclusion leads to the inactivation of one allele of a gene. The active allele is known as ____________

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Q. Both the imprinted genes inherited from either parent are expressed in an offspring.

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Q. De-novo methylation leads to the phenomenon of genetic imprinting in the offspring.

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Q. Major methylation of CpG islands does not include?

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Q. The Intergenic CpGs are more commonly methylated than in the intragenetic region.

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Q. In humans CpG islands are generally located in the ____________

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Q. The CpG islands generally consist of how many GC bases?

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Q. Methylation of cytosine increases the transition mutation of cytosine to __________

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Q. Both de-novo methylation and maintenance methylation ensures the methylation pattern is inherited from parent to daughters.

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