Q. GATC sequence on either side of the mismatch can help in MMR.

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Q. Which DNA polymerase plays a role in repair synthesis in BER in prokaryotes?

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Q. BER detects wrong bases by __________________

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Q. AP endonuclease can cleave the DNA at__________ while AP lyase will cleave the DNA at__________

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Q. Which of the following can’t be repaired by BER?

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Q. Which of the bond in the nucleotide is broken 1st in BER?

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Q. Which of the following will be seen to resolve the flap in eukaryotic short patch BER?

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Q. Which factor works in conjugation with FEN1?

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Q. In an experiment you fuse cells from two patients suffering from XP ( Xeroderma Pigmentosum). The fused cells will be expected to agree to which of the following?

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Q. The bulky lesions in GG-NER is detected by ___________

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Q. Which of the following NER factors is also a subunit of a transcription factor?

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Q. Which of the exonucleases of NER binds to which end of the lesion?

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Q. Which of the DNA polymerase in eukaryotes is responsible for repair synthesis of the excised strand in NER?

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Q. What is the stretch of free DNA needed by NER machinery to repair the bulky lesions in TC NER?

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Q. What is the stretch of free DNA needed by NER machinery to repair the bulky lesions in TC NER?Which of the factors are necessary in TC NER but not in GG NER?

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Q. Which of the factor in prokaryotic NER acts as the helicase?

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Q. Which of the molecule in photolyase acts as an electron donor for recovery of the CPD?

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Q. You radiate a stock of E. Coli with UV rays and another stock is irradiated as control. The 1st stock is seen to be more resistant to alkylating agents. Which gene is expected to be triggered by this UV?

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Q. It is good that Guanine methyl transferase is absent in human beings.

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Q. What is the molecule released in 2nd step of Alk B reaction which returns the base to normal form?

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