Question

Self reactive antibodies are not found in significant concentration in normal serum because

a.

it is impossible to generate a self-reactive antibody

b.

self reactive B cells are killed by CD8 T cells

c.

B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

d.

self reactive B cells switch to IgA which is all secreted and not present in serum

Posted under Antibodies and Immune System Microbiology

Answer: (c).B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

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Q. Self reactive antibodies are not found in significant concentration in normal serum because
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