Q. In some organisms, presence of double stranded RNAs leads to breakdown of corresponding single stranded mRNA.

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Q. Double stranded RNA is cleaved by a nuclease called as Dicer and small fragments are generated known as ___________

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Q. The process of RNA inactivation by siRNAs is termed as ___________

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Q. DNA _________ is also a method for gene silencing through short RNAs.

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Q. siRNAs can either be introduced directly or by microinjection.

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Q. Introduction into host organism can also be done by using a DNA construct, which when transcribed, generates an RNA which is _________

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Q. The ________ protein of bacteriophage P1 mediates site-specific recombination at a 34 bp sequence, loxP.

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Q. Choose the incorrect statement for cre-lox excision.

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Q. Cre can be introduced by crossing it with a strain containing the gene or by infection with virus containing it.

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Q. How much effect is there on the surrounding genes by the loxP sequence which is left after recombination has taken place?

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Q. The ability to control the expression of cre allows controlling what?

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Q. Excision of DNA flanked by loxP sequences is also known as _________

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Q. RNA molecule with catalytic activity is termed as________

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Q. Hepatitis delta virus capable of self cleavage.

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Q. Choose the correct statement for self cleavage reaction.

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Q. Self cleavage reaction can take place in?

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Q. A substance that induces unregulated growth processes in cells or tissues leading to cancer are called as

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Q. Mutagens can be

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Q. Carcinogens are always

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Q. A permanent change of the nucleotide sequence of the genome is called

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