Question

Which of the following about Rb tumor suppressor protein is correct?

a.

It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received

b.

It is activated when phosphorylated by Cdk

c.

It is a transcription factor

d.

When a mitogenic signal is received, it binds the transcription factor E2F and thus stimulates the cell to enter S phase

Answer: (a).It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received

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Q. Which of the following about Rb tumor suppressor protein is correct?

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