Question

Which of the following is false in case of the database Pfam and its algorithm?

a.

Each motif or domain is represented by an HMM profile generated from the seed alignment of a number of conserved homologous proteins

b.

Since the probability scoring mechanism is more complex in HMM than in a profile-based approach the use of HMM yields further increases in sensitivity of the database matches

c.

Pfam-B only contains sequence families not covered in Pfam

d.

The functional annotation of motifs in Pfam-A is often related to that in UNIPROT

Posted under Bioinformatics

Answer: (d).The functional annotation of motifs in Pfam-A is often related to that in UNIPROT

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Q. Which of the following is false in case of the database Pfam and its algorithm?
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