Q. The last step in structure classification involves grouping proteins/domains of similar structures.

View solution

Q. Which of the following is untrue about SCOP?

View solution

Q. Members within the ____ fold ______ have evolutionary relationships.

View solution

Q. In CATH, Structural domain separation is carried by ___________

View solution

Q. Which of the following is untrue about SCOP and CATH?

View solution

Q. SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins.

View solution

Q. CATH is a combination of manual curation and automated procedure, which makes the process less subjective.

View solution

Q. The formation of _____ is determined by ______ interactions, whereas the formation of ____ is strongly influenced by ______ interactions.

View solution

Q. The secondary structure prediction methods can be either ab initio based, which make use of single sequence information only, or homology based, which makes use of multiple sequence alignment information.

View solution

Q. Which of the following is untrue regarding Ab Initio–Based Methods?

View solution

Q. The Chou–Fasman algorithm determines the propensity or intrinsic tendency of each residue to be in the helix, strand, and β-turn conformation using observed frequencies found in protein crystal structures.

View solution

Q. The GOR method is based on the “propensity” of each residue to be in one of the two conformational states, helix (H), strand(E).

View solution

Q. Which of the following is untrue regarding Chou–Fasman and GOR methods?

View solution

Q. Which of the following is untrue regarding Homology-Based Methods?

View solution

Q. Because residues in the same aligned position are assumed to have the same secondary structure, any inconsistencies or errors in prediction of individual sequences can be corrected using a majority rule.

View solution

Q. Which of the following is untrue regarding Prediction with Neural Networks?

View solution

Q. Which of the following is untrue regarding Prediction with Neural Networks?

View solution

Q. Which of the following is untrue regarding Prediction with Neural Networks?

View solution

Q. Which of the following is untrue regarding PHD?

View solution

Q. Which of the following is untrue regarding the transmembrane proteins?

View solution