Q. There exist three types of interactions between domains. Which of the following is not one of them?

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Q. Stable complexes consist of proteins that are _____ associated with each other, like many ____ proteins for instance.

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Q. Sets of proteins that are part of stable complexes and sets of proteins involved in transient interactions ____ in terms of the similarity in gene expression among the set of proteins.

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Q. Correlation of gene expression for pairs of transiently interacting proteins is ______ compared to randomly chosen pairs of proteins.

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Q. Membership in a stable complex also differs from transient interaction in terms of evolutionary constraints upon sequence divergence.

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Q. For proteins in stable complexes the average sequence identity is 46%, while for proteins in transient interactions it is 41%.

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Q. Which of the following is incorrect about Yeast-two-hybrid screens?

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Q. Which of the following is incorrect about Purification of protein complexes followed by mass spectrometry?

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Q. Which of the following is untrue?

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Q. In protein domain family interaction map, the physical contacts of the domains in different families are represented by the lines between the nodes.

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Q. In the Interaction map of domain families, the interactions of one family represent the sum of all the interactions of domains in that family.

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Q. Most domain families only interact with one or two other families, while a few families are extremely versatile in their interactions and are connected to many families.

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Q. Almost ______ engage in interactions with domains from their own family when one includes oligomeric proteins.

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Q. In order to understand the geometry of domain combinations, different structures of homologous pairs of domains must be studied.

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Q. The investigation (Aloy and Russel) of domain combinations in multidomain proteins by Bashton and Chothia focuses on two-domain proteins belonging to the Rossmann domain family.

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Q. The linkers between the catalytic domain and the Rossmann domain were conserved in each family.

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Q. Across the different types of catalytic families, the position of the two domains with respect to one another varied, but only within a range of about ______

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Q. Experimentation is most desirable over computational methods by every means.

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Q. Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______

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Q. Genes that are consistently part of the same operon across different, distantly related genomes are likely to be part of the same protein complex or functional process across all species.

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