Q. In a quantitative assessment of this method (Conservation of gene order) using the genome of the parasitic organism Mycoplasma genitalium as a benchmark.

View solution

Q. Members of a stable complex are often co-regulated and thus will be detected by the method of Conservation of gene order.

View solution

Q. When comparing pairs of genes or sets of genes in different genomes for this purpose, it is not mandatory for the genes to be orthologs.

View solution

Q. Genes that are consistently part of the same operon across different, distantly related genomes are likely to be part of the same protein complex or functional process across all species.

View solution

Q. Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______

View solution

Q. Experimentation is most desirable over computational methods by every means.

View solution

Q. Across the different types of catalytic families, the position of the two domains with respect to one another varied, but only within a range of about ______

View solution

Q. The linkers between the catalytic domain and the Rossmann domain were conserved in each family.

View solution

Q. The investigation (Aloy and Russel) of domain combinations in multidomain proteins by Bashton and Chothia focuses on two-domain proteins belonging to the Rossmann domain family.

View solution

Q. In order to understand the geometry of domain combinations, different structures of homologous pairs of domains must be studied.

View solution

Q. Almost ______ engage in interactions with domains from their own family when one includes oligomeric proteins.

View solution

Q. Most domain families only interact with one or two other families, while a few families are extremely versatile in their interactions and are connected to many families.

View solution

Q. In the Interaction map of domain families, the interactions of one family represent the sum of all the interactions of domains in that family.

View solution

Q. In protein domain family interaction map, the physical contacts of the domains in different families are represented by the lines between the nodes.

View solution

Q. Which of the following is untrue?

View solution

Q. Which of the following is incorrect about Purification of protein complexes followed by mass spectrometry?

View solution

Q. Which of the following is incorrect about Yeast-two-hybrid screens?

View solution

Q. For proteins in stable complexes the average sequence identity is 46%, while for proteins in transient interactions it is 41%.

View solution

Q. Membership in a stable complex also differs from transient interaction in terms of evolutionary constraints upon sequence divergence.

View solution

Q. Correlation of gene expression for pairs of transiently interacting proteins is ______ compared to randomly chosen pairs of proteins.

View solution