Q. According to the pH-partition hypothesis which one of the given options doesn’t govern the absorption?

View solution

Q. If the pH of either side of the membrane is different, then the compartment whose pH favours greater ionization will have less amount of drug.

View solution

Q. Which of the following equations correct for Henderson-Hasselbach equation for weak acids?

View solution

Q. Which of the following equations correct for Henderson-Hasselbach equation for weak bases?

View solution

Q. What is the pH range of the stomach?

View solution

Q. What is the pH range of the intestine?

View solution

Q. Acids in the pKa range 2.5-7.5 are greatly affected by changes in pH making their absorption pH dependent.

View solution

Q. Which one of these is an example of a strong acid drug?

View solution

Q. Which one of these is not an example of a basic drug with pKa range 5-11?

View solution

Q. Example of a drug which has PKa > 11 is ________

View solution

Q. What should be the range of oil/water partition coefficient of any drug?

View solution

Q. Ibuprofen a weak acid, in the stomach will be present in which of the given form?

View solution

Q. Nitrazepam a weak base, will be in which form in the stomach?

View solution

Q. All drugs which are weak acids or acidic in nature will be in a unionized form in the plasma.

View solution

Q. Heroin with pKa 7.8 will be in which form in intestinal pH?

View solution

Q. Which one of these options is not one of the limitations of pH-partition theory?

View solution

Q. A microclimate pH, different from the luminal pH exists at the membrane surface.

View solution

Q. According to the pH-partition theory which form of the drug gets absorbed mostly?

View solution

Q. What helps the ionized drug molecules to pass through the cell membrane passively?

View solution

Q. Acidic drugs are best absorbed through the stomach and basic drugs are best absorbed through the intestine.

View solution