Question

Which one is the correct equation to calculate the fraction of unbound drug in plasma?

a.

Concentration of unbound drug in plasma / total plasma concentration of drug

b.

Total plasma concentration of drug / Concentration of unbound drug in plasma

c.

1/Concentration of unbound drug in plasma

d.

1/total plasma concentration of drug

Answer: (a).Concentration of unbound drug in plasma / total plasma concentration of drug

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Q. Which one is the correct equation to calculate the fraction of unbound drug in plasma?

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