Q. Age, sex, species, differences in genetic makeup alter drug excretion.

View solution

Q. What will be the unbound drug concentration if the unbound drug fraction is 0.52 and the total plasma concentration is 140 g/ml?

View solution

Q. What will be the fraction of unbound drug if the unbound drug concentration is 0.99 g/ml and total plasma concentration is 160 g/ml?

View solution

Q. Which one is the correct equation to calculate the fraction of unbound drug in plasma?

View solution

Q. Which drugs cannot be filtered through glomerulus?

View solution

Q. Clearance is inversely related to volume of distribution.

View solution

Q. Drugs of molecular range 300-500 Dalton will be excreted out by glomerulus.

View solution

Q. Which of the following is not a physicochemical factor of drug that can affect the renal excretion?

View solution

Q. Which of the following is not a factor of renal excretion?

View solution

Q. What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?

View solution

Q. How do you calculate the rate of excretion by kidneys?

View solution

Q. What will be the renal clearance ratio of a drug whose renal clearance is 40ml/min and the clearance of creatinine is 95ml/min?

View solution

Q. How renal clearance ratio is expressed?

View solution

Q. What will be the renal clearance if the rate of urinary excretion is 625 ml/min and plasma drug concentration is 4.2 ng/ml?

View solution

Q. What will be the elimination rate if the clearance is 130ml/min and drug concentration is 0.8 g/ml?

View solution

Q. What is the equation for clearance?

View solution

Q. What is total systemic clearance?

View solution

Q. The rate of urine flow influences the extent of reabsorption.

View solution

Q. Which of the following compounds are used as agents to determine Glomerular Filtration Rate?

View solution

Q. What is the driving force for glomerular filtration?

View solution