Q. Which of the following compounds are used as agents to determine Glomerular Filtration Rate?

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Q. The rate of urine flow influences the extent of reabsorption.

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Q. What is total systemic clearance?

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Q. What is the equation for clearance?

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Q. What will be the elimination rate if the clearance is 130ml/min and drug concentration is 0.8 g/ml?

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Q. What will be the renal clearance if the rate of urinary excretion is 625 ml/min and plasma drug concentration is 4.2 ng/ml?

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Q. How renal clearance ratio is expressed?

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Q. What will be the renal clearance ratio of a drug whose renal clearance is 40ml/min and the clearance of creatinine is 95ml/min?

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Q. How do you calculate the rate of excretion by kidneys?

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Q. What will be the rate of filtration if the rate of secretion is 0.9 ml/ sec, rate of reabsorption is 0.2 ml/sec and the rate of excretion is 2ml/sec for a particular drug?

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Q. Which of the following is not a factor of renal excretion?

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Q. Which of the following is not a physicochemical factor of drug that can affect the renal excretion?

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Q. Drugs of molecular range 300-500 Dalton will be excreted out by glomerulus.

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Q. Clearance is inversely related to volume of distribution.

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Q. Which drugs cannot be filtered through glomerulus?

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Q. Which one is the correct equation to calculate the fraction of unbound drug in plasma?

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Q. What will be the fraction of unbound drug if the unbound drug concentration is 0.99 g/ml and total plasma concentration is 160 g/ml?

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Q. What will be the unbound drug concentration if the unbound drug fraction is 0.52 and the total plasma concentration is 140 g/ml?

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Q. Age, sex, species, differences in genetic makeup alter drug excretion.

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Q. Which bond should be between the active drug and inert carrier?

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