Q. What is meant by elimination half-life?

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Q. What is the equation to find out the apparent volume of distribution?

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Q. The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

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Q. To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?

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Q. What is the equation to find out hepatic clearance?

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Q. Which organs comprise the central compartment in a two compartment model?

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Q. Which organ comprises the peripheral compartment in a two compartment model?

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Q. Which of the following is not a category of 2 compartment model?

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Q. Any changes in fraction bioavailable, elimination half-life indicates nonlinearity of that particular drug.

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Q. Which of the following creates nonlinearity in drug distribution and not in drug absorption?

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Q. Which one of these are correct Michaelis-Menten equation?

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Q. What is bioavailability?

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Q. What is the equation of bioavailable fraction?

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Q. Which of the following is not an objective of bioavailability studies?

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Q. Single-dose bioavailability studies are simple and common.

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Q. Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.

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Q. Which of the following is the pharmacodynamics method of studying bioavailability?

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Q. Which of the following is not an important parameter of plasma level time studies?

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Q. What is the equation for bioavailability?

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Q. The urinary excretion of the unchanged drug is directly proportional to the plasma concentration of a drug.

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