Q. Binding of the large subunit to the small subunit triggers a cascade of reactions. Arrange them in order of their occurrence.

i. Release of IF1
ii. Hydrolysis of IF2-GTP
iii. Formation of vacant A site
iv. Reduced affinity of IF2-GDP

View solution

Q. For the correct addition of amino acid to the growing polypeptide chain which of the following does not play any role?

View solution

Q. The events controlling the correct addition of amino acid is controlled by ____________ proteins.

View solution

Q. The auxillary protein required for the elongation of polypeptide is energy independent.

View solution

Q. Aminoacyl tRNA needs an escort to carry them to the ribosome bound mRNA.

View solution

Q. Once the tRNA is aminoacylated, EF-Tu binds to the tRNA at the ____________

View solution

Q. The activation of GTPase activity of the enzyme EF-Tu occurs after its binding to the aminoacylated tRNA.

View solution

Q. The only fidelity testing of the translation is by observing the energy difference involved in the correct and incorrect base pairing.

View solution

Q. How many mechanisms are involved in the maintenance of the fidelity of translation?

View solution

Q. Which part of the large subunit helps in the formation of the peptide bond?

View solution

Q. Which of the following steps is not required for the process of translocation?

View solution

Q. The completion of translocation requires the action of the factor _________________

View solution

Q. The subunit association with the mRNA occurs before tRNA recruitment in the case of both eukaryotes and prokaryotes.

View solution

Q. Eukaryotic mRNA generally codes for a single protein because the eukaryotic translation includes ____________

View solution

Q. The same number of auxiliary proteins is used to drive the initiation process of both prokaryotes and eukaryotes.

View solution

Q. The first amino acid to be incorporated in the eukaryotic polypeptide is ___________

View solution

Q. Which of the following eukaryotic proteins is an analog of IF2-GTP?

View solution

Q. Recognition of mRNA by 43S pre-initiation complex is mediated by the enzyme ___________

View solution

Q. Which of the following protein interacts with the eIF4F for recruiting the pre-initiation complex to the mRNA?

View solution

Q. mRNA scanning is a cost-effective mechanism.

View solution