Q. Inactive miRNA undergoes how many cleavages before incorporation into the RISC complex?

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Q. piRNAs are synthesized in a Dicer dependent mechanism.

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Q. Stem loop precursors are generally seen in which of the following?

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Q. Methylation at which of the following bases is possible within the following oligonucleotides?

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Q. Which is known to be methylated in eukaryotic cells?

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Q. Among the following which shows the maximum rate of cytosine methylation?

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Q. The region of maximum methylation in the genome is predominantly activated.

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Q. Prokaryotic methylation occurs at ____________

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Q. How many types of methylation processes are known in eukaryotic cells?

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Q. De-novo methylation is done in the newly synthesized DNA strand at opposite positions of the methylated sites on the parent strand.

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Q. Both de-novo methylation and maintenance methylation ensures the methylation pattern is inherited from parent to daughters.

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Q. Methylation of cytosine increases the transition mutation of cytosine to __________

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Q. The CpG islands generally consist of how many GC bases?

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Q. In humans CpG islands are generally located in the ____________

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Q. The Intergenic CpGs are more commonly methylated than in the intragenetic region.

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Q. Major methylation of CpG islands does not include?

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Q. De-novo methylation leads to the phenomenon of genetic imprinting in the offspring.

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Q. Both the imprinted genes inherited from either parent are expressed in an offspring.

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Q. The phenomenon of allelic exclusion leads to the inactivation of one allele of a gene. The active allele is known as ____________

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Q. `11

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