Q. In an experiment you add rifampicin and paramomycin to the ribosome and mRNA mixture. What will inhibit theribosomal translation efficiency and how?

View solution

Q. Which antibiotic inhibits peptidyl transfer by blocking the accommodation of aa-tRNA into the peptidyl transferase (A/A) site?

View solution

Q. Which of the antibiotic can halt translocation of the ribosome bound to the mRNA?

View solution

Q. The ribosome slides over the mRNA translating it.

View solution

Q. In an experiment you add streptomycin at low concentration first and then gradually increase the concentration till it completely inhibits peptide formation. What will be its effect at low concentration?

View solution

Q. What will be DNA sequence of Shine and Dalgarno coding region?

View solution

Q. In an experiment you grow some cells in a media containing heavy isotopes of C and N. Then you transfer then to a lighter media. If you centrifuge the ribosomes so obtained after an hour how many bands will you expect?

View solution

Q. In an experiment you stall the ribosome with low Mg²⁺ concentration. Which of the following will then cause the release of the Peptide from the ribosome?

View solution

Q. What discovery was stated by Robert Traut and Munro experiment?

View solution

Q. What was the unnatural experimental condition which proved to be a criticism in Robert Traut and Munro experiment?

View solution

Q. Which of the following was not a protein degrading agent used by Noller in his experiment?

View solution

Q. You gradually treat ribosome with SDS followed by Proteinase K and the finally extract it with phenol. Which of the options match the result you expect?

View solution

Q. How many proteins were still intact after the treatment of ribosome with SDS and proteinase K?

View solution

Q. What is the distance between the catalytic site and the nearest protein in the ribosome?

View solution

Q. Tetracyclin is only harmful to prokaryotes.

View solution

Q. Aminoglycosides can kill_______________

View solution

Q. In evolutionary history which of the following rose 1st?

View solution

Q. The 16S rRNA binds the mRNA in its ___________ region.

View solution

Q. _____________ treated ribosomes will be able to carry out elongation and termination of previously initiated translation, but can’t initiate any new translation.

View solution

Q. IF1 helps in correct placement of the initiation tRNA. How does it do so?

View solution