Q. Translation of which sigma factor is dependent on a genetic thermostat?

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Q. In an experiment if you take a stretch of hybridized RNA, and add only eIF4A, eIF4B and eIF4a and eIF4B together what will happen to the band obtained by that fragment under SDS.

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Q. The production of casein by rat mammary gland tissue reduces 100 fold in the absence of prolactin hormone. This reduction is due to_____________

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Q. When the intracellular iron level is low, the turnover of transferrin mRNA is________

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Q. In a synergistic model of initiation which of the following factor doesn’t directly lead to initiation?

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Q. Which of the following acts as a GAP during translation?

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Q. In an experiment with the effect of insulin on the protein synthesis, which of the factors doesn’t play a role?

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Q. Mitogens can control translation efficiency by acting on _____________ factor which ___________

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Q. IRE-BP does not bind to _______________

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Q. The AU rich regions on the stem loop structure of IRE ____________

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Q. In Eukaryotes the region between 1st AUG and 5’-G cap is known as ___________

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Q. Which of the following will effectively cause normal translation from an initiation AUG, blocked by a strong AUG upstream?

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Q. A frame shift mutation can lead to alternate proteins.

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Q. What is the final factor in eukaryotes that releases the peptide and ribosome?

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Q. During translation RF1 recognizes the stop codon UGA and translation come to a halt as RF3 is called in.

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Q. EF2 structurally mimics_______

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Q. The eukaryotic initiation codon recognizes________

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Q. What is the eukaryotic homologue for EF-G?

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Q. Which factors lead to disassociation of the ribosomal subunits?

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Q. Which factor or factors lead to the ultimate disassembly of the ribosomal complex?

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