Q. In Drosophila Crossing over in paracentric region is lethal and leads to cross-over suppression. This leads to reduction in fertility.

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Q. Long pericentric inversions generally don’t act as cross over suppressors. Why?

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Q. Choose the wrong option.

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Q. In drosophila male there is no cross over suppression due to pericentric inversion as___________

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Q. Which of the following is an example of inversion?

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Q. In pericentric inversion, the inversion loop involves __________ strands.

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Q. Which of the following case of duplication involves more than one chromosome?

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Q. Tandem duplication creates ____________ and reverse tandem creates_____________

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Q. The Streisinger’s model explains__________

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Q. If there are two sequences CGCGCGCG and ATATATAT, which will have a higher probability of being duplicated?

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Q. Which of the following will have the highest number of eye facete?

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Q. Duplication of Vermillion eye colour gene leads to the expression of the mutant phenotype. Which of the following can lead to normal phenotype with this duplication present?

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Q. Which human chromosomes are involved in Down’s syndrome?

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Q. Which of the following could be due to duplication?

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Q. If a gene undergoes duplication and one of the duplicated copy is mutated to render unexpressed protein. What will be the effect on phenotype?

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Q. During Strisinger’s model, what happens?

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Q. Deletion in sex chromosome is better tolerated than that in autosome.

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Q. How will you recognize a terminal deletion from breakage and loss at the terminal end?

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Q. What will be the effect of the deletion mutation of a gene at the telomere?

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Q. You hybridize two cells one of which carries a deletion mutation on chromosome 1. What will you expect to observe?

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