Question

If rotenone is added to the mitochondrial electron transport chain

a.

Succinate oxidation remains normal

b.

P: O ratio of NADH is reduced from 3:1 to 2:1

c.

Oxidative phosphorylation is uncoupled at site I

d.

Rate of NADH oxidation is diminished to two-thirds of its initial value

Posted under Biochemistry

Answer: (a).Succinate oxidation remains normal

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Q. If rotenone is added to the mitochondrial electron transport chain

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