Q. VAST is a web server that performs alignment using intramolecular approaches only.

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Q. The classification results from both systems, SCOP and CATH are quite dissimilar.

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Q. The first step in structure classification is to remove redundancy from databases.

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Q. The second step in structure classification is to separate structurally distinct domains within a structure.

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Q. The last step in structure classification involves grouping proteins/domains of similar structures.

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Q. Which of the following is untrue about SCOP?

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Q. Members within the ____ fold ______ have evolutionary relationships.

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Q. In CATH, Structural domain separation is carried by ___________

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Q. Which of the following is untrue about SCOP and CATH?

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Q. SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins.

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Q. CATH is a combination of manual curation and automated procedure, which makes the process less subjective.

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Q. The formation of _____ is determined by ______ interactions, whereas the formation of ____ is strongly influenced by ______ interactions.

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Q. The secondary structure prediction methods can be either ab initio based, which make use of single sequence information only, or homology based, which makes use of multiple sequence alignment information.

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Q. Which of the following is untrue regarding Ab Initio–Based Methods?

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Q. The Chou–Fasman algorithm determines the propensity or intrinsic tendency of each residue to be in the helix, strand, and β-turn conformation using observed frequencies found in protein crystal structures.

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Q. The GOR method is based on the “propensity” of each residue to be in one of the two conformational states, helix (H), strand(E).

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Q. Which of the following is untrue regarding Chou–Fasman and GOR methods?

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Q. Which of the following is untrue regarding Homology-Based Methods?

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Q. Because residues in the same aligned position are assumed to have the same secondary structure, any inconsistencies or errors in prediction of individual sequences can be corrected using a majority rule.

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Q. Which of the following is untrue regarding Prediction with Neural Networks?

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