Q. The main issue in prediction of eukaryotic genes is the identification of exons, introns, and splicing sites.

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Q. Most vertebrate genes use __________ as the translation start codon and have a uniquely conserved flanking sequence call a Kozak sequence (CCGCCATGG).

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Q. Which of the following is untrue about Ab Initio–Based Programs for Gene Prediction?

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Q. In Ab Initio–Based Programs for Gene Prediction– Gene content refers to coding statistics, which includes nonrandom nucleotide distribution, amino acid distribution, synonymous codon usage, and hexamer frequencies.

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Q. Which of the following is untrue about PredictionUsing NeuralNetworks for Gene Prediction?

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Q. Which of the following is untrue about Prediction Using Neural Networks for Gene Prediction?

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Q. GRAIL is a web-based program that is based on a neural network algorithm Which is trained on several statistical features such as splice junctions, start and stop codons, poly-A sites, promoters, and CpG islands.

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Q. Which of the following is untrue about Prediction Using Discriminant Analysis for Gene Prediction?

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Q. Which of the following is untrue about FGENES?

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Q. GENSCAN is awebbased program that makes predictions based on fifth-order HMMs.

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Q. Which of the following wrong about HMM GENE?

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Q. Which of the following is untrue about Homology-Based Programs?

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Q. The drawback of Homology-based approach is its reliance on the presence of homologs in databases.

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Q. GenomeScan is a web-based server that combines GENSCAN prediction results with BLASTX similarity searches.

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Q. Which of the following is untrue about EST2Genome?

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Q. Which of the following is untrue about SGP-1?

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Q. TwinScan is also a similarity-based gene-finding Server and it is similar to GenomeScan in that it uses GenScan to predict all possible exons from the genomic sequence.

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Q. Because different prediction programs have different levels of sensitivity and specificity, it makes sense to combine results of multiple programs based on consensus. This idea has prompted development of consensus-based algorithms.

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Q. In bacteria, transcription is initiated by DNA polymerase.

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Q. The upstream sequence where the σ protein binds constitutes the promoter sequence.

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