Q. In the program COGNITOR each protein in the proteome is used as a query of a database of protein clusters.

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Q. WU-BLAST produces P scores and BLAST (NCBI) produces E scores where _________

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Q. In Proteolysis and fragment sequencing, Protein spots may be excised from a two-dimensional protein gel and subjected to a combination of amino acid sequencing and cleavage analyses using the techniques of mass spectrometry and high-pressure liquid chromatography.

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Q. In Protein 2D gel Electrophoresis, Individual proteins produced by the genome can be separated to _____ by this method and specific ones identified by various _______

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Q. In Metabolic pathways and regulation, as genes are identified in a new genome sequence, some will be found that are known to act sequentially in a metabolic pathway or to have a known role in gene regulation in other organisms.

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Q. _______ of the Drosophila sequence is composed of TEs and _____ is heterochromatic regions that do not include genes.

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Q. Yeast is about ______ compact than E. coli.

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Q. The ________ are _______ by genetic structure to retroviruses.

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Q. Which of the given statement is incorrect?

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Q. The higher the E value, the more significant the alignment between a pair of matching sequences.

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Q. Which of the given statement is incorrect about proteome analyses?

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Q. An all-against-all analysis requires first making a database of the proteome. This database is then sequentially searched by each individual protein sequence of the proteome using a rapid database similarity search tool such as _______

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Q. Evolutionary modeling can include various types of analyses. Which is mostly not one of them?

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Q. Which of the given statement is incorrect about Clusters of functionally related genes?

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Q. Which of the given statement is incorrect about Orthologs?

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Q. In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.

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Q. In all-against-all self comparison, A comparison is made in which every protein is used as a query in a similarity search against a database composed of the rest of the proteome, and the significant matches are identified by a low expect value.

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Q. Processed pseudogenes are also derived from a functional gene and they contain introns and a promoter.

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Q. Pseudogenes are DNA sequences that were derived from distinct genes but which have acquired mutations that are deleterious to function in the same period of time.

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Q. New gene functions are thought to be gained by duplication of an existing gene creating two tandem copies.

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