Question
a.
Paralogs may include a best hit or a high-scoring match of one of the sequences by another, but the reciprocal match can have low similarity that does not have to be significant
b.
Paralogs defined by sets of three matching sequences in the selected organisms were kept separated from the clusters
c.
Orthologous pairs were first defined by the best hits in reciprocal searches
d.
To produce COGs, similarity searches were performed among the proteomes of phylogenetically distinct clades of prokaryotes
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Q. Which of the given statements is incorrect about Clusters of orthologous groups?
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