Prodrugs and Excretion of Drugs MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Prodrugs and Excretion of Drugs, a fundamental topic in the field of Drug and Pharmaceutical Biotechnology. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Prodrugs and Excretion of Drugs MCQs are designed to help you grasp the core concepts and excel in solving problems.

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Prodrugs and Excretion of Drugs MCQs | Page 6 of 7

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Q51.
What will be the fraction of unbound drug if the unbound drug concentration is 0.99 g/ml and total plasma concentration is 160 g/ml?

a.

0.006

b.

1.61

c.

0.618

d.

0.010

Discuss
Answer: (c).0.618
Q52.
What will be the unbound drug concentration if the unbound drug fraction is 0.52 and the total plasma concentration is 140 g/ml?

a.

80 g/ml

b.

82.8 g/ml

c.

70 g/ml

d.

72.8 g/ml

Discuss
Answer: (d).72.8 g/ml
Q53.
Age, sex, species, differences in genetic makeup alter drug excretion.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q54.
Which bond should be between the active drug and inert carrier?

a.

Covalent bond

b.

Vander Waal’s force

c.

Di-sulphide bond

d.

Ionic bond

Discuss
Answer: (a).Covalent bond
Q55.
What is the prodrug of Trichloroethanol Cl₃C-CH₂OH?

a.

a

b.

b

c.

c

d.

d

Discuss
Answer: (b).b
Q56.
In the following diagram which organ name should be in the place of ‘?’?

a.

Small intestine

b.

Large intestine

c.

Liver

d.

Kidney

Discuss
Answer: (a).Small intestine
Q57.
In a graph of rate of excretion versus plasma drug concentration, which kind of drug will give the below shown curve?

a.

Drug excreted only by filtration

b.

Drug filtered and actively reabsorbed

c.

Drug filtered as well as actively secreted

d.

Drug reabsorbed actively

Discuss
Answer: (a).Drug excreted only by filtration
Q58.
In a graph of rate of excretion versus plasma drug concentration, which kind of drug will give the below shown curve?

a.

Drug excreted only by filtration

b.

Drug filtered and actively reabsorbed

c.

Drug filtered as well as actively secreted

d.

Drug reabsorbed actively

Discuss
Answer: (c).Drug filtered as well as actively secreted
Q59.
In a graph of rate of excretion versus plasma drug concentration, which kind of drug will give the below shown curve? (x axis- rate of excretion, y axis – plasma drug concentration)

a.

Drug excreted only by filtration

b.

Drug filtered and actively reabsorbed

c.

Drug filtered as well as actively secreted

d.

Drug reabsorbed actively

Discuss
Answer: (b).Drug filtered and actively reabsorbed
Q60.
In a graph of renal clearance versus plasma drug concentration, which kind of drug will give the below shown curve?

a.

Drug excreted only by filtration

b.

Drug filtered and actively reabsorbed

c.

Drug filtered as well as actively secreted

d.

Drug reabsorbed actively

Discuss
Answer: (a).Drug excreted only by filtration
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