Q. With the application of Bayesian methods, the most probable repeat length and evolutionary time since the repeat was formed may be derived.

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Q. If the purpose is to calculate the probability of one event AND a second event, the odds scores for the events are _________

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Q. In a type of probability, analysis is to calculate the odds score for one event OR a second event, or of a series of events. In this case, the odds scores are _______

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Q. In Bayesian methods, difficulty with making estimations is that the estimate depends on the following Assumption.
(Assumption – The mutation rate in sequences has been constant with time and that the rate of mutation of all nucleotides is the same.)

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Q. Another difficulty in Bayesian methods is deciding on the length of sequence that was duplicated.

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Q. A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________

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Q. Which of the following feature of Bayesian methods is the disadvantage of it?

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Q. Zhu (1998) have devised a computer program called the Bayes block aligner which in effect slides ____ sequences along each other to find the ______ ungapped regions or blocks.

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Q. Unlike the commonly used methods for aligning a pair of sequences, the Bayesian method _______ using a particular scoring matrix or designated gap penalties.

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Q. Which of the following is incorrect regarding pair wise sequence alignment?

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Q. Which of the following is incorrect about evolution?

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Q. The presence of evolutionary traces is because some of the residues that perform key functional and structural roles tend to be preserved by natural selection; other residues that may be less crucial for structure and function tend to mutate more frequently.

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Q. The degree of sequence variation in the alignment reveals evolutionary relatedness of different sequences, whereas the conservation between sequences reflects the changes that have occurred during evolution in the form of substitutions, insertions, and deletions.

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Q. If the two sequences share significant similarity, it is extremely ______ that the extensive similarity between the two sequences has been acquired randomly, meaning that the two sequences must have derived from a common evolutionary origin.

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Q. Sometimes, it is also possible that two sequences have derived from a common ancestor, but may have diverged to such an extent that the common ancestral relationships are not recognizable at the sequence level.

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Q. Which of the following is incorrect regarding sequence homology?

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Q. Sequence similarity can be quantified using ________ homology is a ______ statement.

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Q. Shorter sequences require higher cutoffs for inferring homologous relationships than longer sequences.

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Q. Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.

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Q. The overall goal of pair wise sequence alignment is to find the best pairing of two sequences, such that there is maximum correspondence among residues.

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