Q. In Rosetta, The segments with assigned _______ structures are subsequently assembled into a ______ dimensional configuration.

View solution

Q. There are a large number of protein folds available, compared to millions of protein sequences.

View solution

Q. Threading or structural fold recognition predicts the structural fold of an unknown protein sequence by fitting the sequence into a structural database and selecting the best-fitting fold.

View solution

Q. The algorithms used here can be classified into two categories, pairwise energy based and profile based.

View solution

Q. In the pairwise energy based method, a protein sequence is searched for in a structural fold database to find the best matching structural fold using ______ criteria.

View solution

Q. The next step in the pairwise energy based method is to build a crude model for the target sequence by replacing aligned residues in the template structure with the corresponding residues in the query.

View solution

Q. Which of the following is untrue about profile method?

View solution

Q. Because threading and fold recognition detect structural homologs ________ relying on sequence similarities, they have been shown to be _______ than PSI-BLAST in finding distant evolutionary relationships

View solution

Q. Which of the following is untrue about threading and fold recognition?

View solution

Q. Which of the following is untrue about 3D-PSSM?

View solution

Q. Which of the following is true about Gen Threader?

View solution