Q. The comparative approach uses basic RNA structure based predictions to infer a consensus structure.

View solution

Q. To distinguish the conserved secondary structure among multiple related RNA sequences, a concept of “covariation” is used.

View solution

Q. ___________ of covariation can be ___________ to the RNA structure and functions.

View solution

Q. An aspect of the comparative method is to select a __________ structure through consensus drawing.

View solution

Q. The comparative-based algorithms can be further divided into two categories based on the type of input data.

View solution

Q. The type of algorithm that requires predefined alignment, requires the user to provide _______ alignment as input.

View solution

Q. The type of algorithm that _____ predefined alignment is ______ for reasonably conserved sequences.

View solution

Q. The predefined alignment requiring method also depends on the quality of the input alignment. If there ___ errors in the alignment, covariation signals ____ detected.

View solution

Q. Which of the following is true about the RNAalifold?

View solution

Q. Rigorously evaluating the performance of RNA prediction programs has traditionally been hindered by the dearth of three-dimensional structural information for RNA.

View solution

Q. If prediction accuracy can be represented using a ______ the ______ programs score roughly 20% to 60% depending on the length of the sequences.

View solution

Q. For _________ RNA sequences, such as tRNA, some programs may be able to produce _________% accuracy.

View solution

Q. The pre-alignment independent programs fare __________ for predicting long sequences.

View solution

Q. Based on recent benchmark comparisons, the comparative-type algorithms can reach an accuracy range of 20% to 80%.

View solution

Q. In comparative approach to RNA structure prediction, algorithms that do not use pre-alignment, align multiple input sequences and infers a consensus structure.

View solution

Q. In comparative approach to RNA structure prediction, Foldalign is a web-based only program for RNA alignment

View solution

Q. In comparative approach to RNA structure prediction, the Foldalign program doesn’t use the covariation information.

View solution

Q. In comparative approach to RNA structure prediction, Dynalign is a ________ program.

View solution

Q. In comparative approach to RNA structure prediction, in Dynalign program–by comparing _________ from each sequence, a ______ structure common to both sequences is selected that serves as the basis for sequence alignment.

View solution

Q. Which of the following is incorrect about the RNA structure prediction?

View solution