Q. ExPASY is a comprehensive proteomics web server with a suite of programs for searching peptide information from the SWISS-PROT and TrEMBL databases.

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Q. Which of the following is incorrect regarding Mascot and ProFound?

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Q. Which of the following is incorrect regarding Differential In-Gel Electrophoresis?

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Q. Which of the following is a wrong statement?

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Q. Which of the following is a wrong about AutoMotif?

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Q. It is important to use bioinformatics tools to predict sites for posttranslational modifications based on specific protein sequences. However, prediction of such modifications can often be difficult because the short lengths of the sequence motifs associated with certain modifications.

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Q. To minimize false-positive results, a statistical learning process called support vector machine (SVM) can be used to increase the specificity of prediction.

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Q. In a statistical learning process called support vector machine (SVM), a hyperplane is _____

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Q. A disulfide bridge is a unique type of _____ modification in which _____ bonds are formed between cysteine residues.

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Q. Accurate prediction of _____ bonds may also help to predict the _____ dimensional structure of the protein of interest.

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Q. Only Advanced neural networks are used to discern long-distance pairwise interactions among cysteine residues.

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Q. Cysteine doesn’t make predictions by building profiles.

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Q. ExPASY contains a number of programs to determine posttranslational modifications based on MS molecular mass data.

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Q. Which of the following is an incorrect statement about the terminologies related to protein sorting?

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Q. For many eukaryotic proteins, newly synthesized protein precursors have to be transported to specific membrane-bound compartments and be proteolytically processed to become functional.

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Q. Once the proteins are translocated within the organelles, protease cleavage takes place to remove the signal sequences and generate mature proteins.

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Q. The signal sequences have a _________ consensus but contain some specific features. They all have a ______ core region preceded by one or more positively charged residues.

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Q. The signal sequences are typically _______ residues long, rich in _____ charged residues such as arginines as well as hydroxyl residues such as serines and threonines, but devoid of ______ charged residues.

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Q. Chloroplast localization signals are also located in the __________ terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine.

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Q. Chloroplast localization signals consist of two adjacent signal peptides, one for targeting the proteins to the stromaportion of the chloroplast before being cleaved and the other for targeting the remaining portion of the proteins to the thylakoids.

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