Antigens and Immune Response MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Antigens and Immune Response, a fundamental topic in the field of Biochemistry. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Antigens and Immune Response MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Antigens and Immune Response mcq questions that explore various aspects of Antigens and Immune Response problems. Each MCQ is crafted to challenge your understanding of Antigens and Immune Response principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Biochemistry tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Antigens and Immune Response MCQs are your pathway to success in mastering this essential Biochemistry topic.

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Antigens and Immune Response MCQs | Page 8 of 10

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Q71.
To detect a humoral immune response to influenza virus, it is possible to measure

a.

cytotoxicity of virus-infected cells in tissue culture

b.

dividing T cells in the draining lymph nodes

c.

plasma cytokine levels

d.

serum antibody titer

Discuss
Answer: (d).serum antibody titer
Q72.
Which of the following is in the lymph nodes of a person battling a cold virus?

a.

Huge numbers of white blood cells

b.

Trapped viruses that have been roaming the body

c.

Lymph ducts that enter and exit the nodes and Lymph fluid

d.

All of the above

Discuss
Answer: (d).All of the above
Q73.
A selective IgA deficiency would be expected to result in problems with

a.

bacterial infections

b.

infections following dental work due to bacteria entering the bloodstream

c.

mucosal pathogens

d.

pathogens which can survive inside macrophages

Discuss
Answer: (c).mucosal pathogens
Q74.
Combined cellular and humoral immune deficiencies result from lack of all of the following except

a.

a thymus

b.

class II MHC

c.

HIV infection of CD4+ T cells

d.

transporter of antigen peptides (TAP)

Discuss
Answer: (d).transporter of antigen peptides (TAP)
Q75.
An example of an immunodeficiency disorder is

a.

thyroiditis

b.

rheumatic fever

c.

systemic lupus erythematosus

d.

AIDS

Discuss
Answer: (d).AIDS
Q76.
Bone marrow given to an infant with SCID must

a.

be irradiated to eliminate GVHD

b.

contain mature T cells that can begin making immune responses immediately

c.

come from a donor that shares some MHC alleles with the recipient

d.

come from one of the child's parents

Discuss
Answer: (c).come from a donor that shares some MHC alleles with the recipient
Q77.
X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

a.

activation of B cells by T-independent antigens

b.

failure of B cells to provide co-stimulation for Th2 activation

c.

failure of Th2 cells to provide co-stimulation for B cell isotype switching

d.

failure of Th2 cells to provide co-stimulation for B cell proliferation

Discuss
Answer: (c).failure of Th2 cells to provide co-stimulation for B cell isotype switching
Q78.
The HIV virus infects primarily

a.

brain cells

b.

cells in the immune system

c.

red blood cells

d.

liver cells

Discuss
Answer: (b).cells in the immune system
Q79.
Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

a.

CTL killing of viruses

b.

dendritic cell activation to become a mature APC

c.

infected cell processing of virus peptides

d.

macrophage intracellular killing of bacteria

Discuss
Answer: (d).macrophage intracellular killing of bacteria
Q80.
Difficulties with somatic gene therapy arise from all of the following except

a.

GVHD caused by mature T cells in the transplanted cells

b.

inserting a gene so that it will function properly

c.

limited life span of more mature hematopoietic cells

d.

transducing genetic material into stem cells

Discuss
Answer: (a).GVHD caused by mature T cells in the transplanted cells
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