Q. The RNAi mediated gene silencing is an ATP-dependent procedure.

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Q. If the siRNA is a complete homolog of the target mRNA sequences what is the net result?

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Q. Binding of siRNA to the DNA does not lead to __________

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Q. Which of the following RNAs can induce gene silencing?

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Q. The miRNAs are transcribed from non-protein encoding genes and are typically __________ nucleotides long.

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Q. The first miRNA was identified in C. elegans named __________

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Q. Pick the odd one out.

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Q. Inactive miRNA undergoes how many cleavages before incorporation into the RISC complex?

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Q. piRNAs are synthesized in a Dicer dependent mechanism.

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Q. Stem loop precursors are generally seen in which of the following?

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Q. Methylation at which of the following bases is possible within the following oligonucleotides?

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Q. Which is known to be methylated in eukaryotic cells?

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Q. Among the following which shows the maximum rate of cytosine methylation?

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Q. The region of maximum methylation in the genome is predominantly activated.

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Q. Prokaryotic methylation occurs at ____________

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Q. How many types of methylation processes are known in eukaryotic cells?

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Q. De-novo methylation is done in the newly synthesized DNA strand at opposite positions of the methylated sites on the parent strand.

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Q. Both de-novo methylation and maintenance methylation ensures the methylation pattern is inherited from parent to daughters.

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Q. Methylation of cytosine increases the transition mutation of cytosine to __________

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Q. The CpG islands generally consist of how many GC bases?

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