Question
a.
The limited knowledge of protein folding forms the basis of ab initio prediction
b.
The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone without the aid of known protein structures
c.
The ab initio prediction method attempts to produce all-atom protein models based on sequence information alone with some aid of known protein structures
d.
The perceived advantage of this method is that predictions are not restricted by known folds and that novel protein folds can be identified
Posted under Structural Bioinformatics Bioinformatics
Interact with the Community - Share Your Thoughts
Uncertain About the Answer? Seek Clarification Here.
Understand the Explanation? Include it Here.
Q. Which of the following is untrue about Ab initio prediction?
Similar Questions
Explore Relevant Multiple Choice Questions (MCQs)
Q. The prediction programs are thus designed using the energy minimization principle.
View solution
Q. Searching for a fold with the absolute minimum energy may not be valid in reality.
View solution
Q. Rosetta is a web server that predicts protein three-dimensional conformations using the ab initio method.
View solution
Q. In Rosetta, The segments with assigned _______ structures are subsequently assembled into a ______ dimensional configuration.
View solution
Q. There are a large number of protein folds available, compared to millions of protein sequences.
View solution
Q. Threading or structural fold recognition predicts the structural fold of an unknown protein sequence by fitting the sequence into a structural database and selecting the best-fitting fold.
View solution
Q. The algorithms used here can be classified into two categories, pairwise energy based and profile based.
View solution
Q. In the pairwise energy based method, a protein sequence is searched for in a structural fold database to find the best matching structural fold using ______ criteria.
View solution
Q. The next step in the pairwise energy based method is to build a crude model for the target sequence by replacing aligned residues in the template structure with the corresponding residues in the query.
View solution
Q. Which of the following is untrue about profile method?
View solution
Q. Because threading and fold recognition detect structural homologs ________ relying on sequence similarities, they have been shown to be _______ than PSI-BLAST in finding distant evolutionary relationships
View solution
Q. Which of the following is untrue about threading and fold recognition?
View solution
Q. Which of the following is untrue about 3D-PSSM?
View solution
Q. Which of the following is true about Gen Threader?
View solution
Recommended Subjects
Are you eager to expand your knowledge beyond Bioinformatics? We've handpicked a range of related categories that you might find intriguing.
Click on the categories below to discover a wealth of MCQs and enrich your understanding of various subjects. Happy exploring!
