Protein Biomolecular Interactions MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Protein Biomolecular Interactions, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Protein Biomolecular Interactions MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Protein Biomolecular Interactions mcq questions that explore various aspects of Protein Biomolecular Interactions problems. Each MCQ is crafted to challenge your understanding of Protein Biomolecular Interactions principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Protein Biomolecular Interactions MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Protein Biomolecular Interactions. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

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Protein Biomolecular Interactions MCQs | Page 2 of 7

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Q11.
The investigation (Aloy and Russel) of domain combinations in multidomain proteins by Bashton and Chothia focuses on two-domain proteins belonging to the Rossmann domain family.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q12.
The linkers between the catalytic domain and the Rossmann domain were conserved in each family.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q13.
Across the different types of catalytic families, the position of the two domains with respect to one another varied, but only within a range of about ______

a.

20°

b.

10°

c.

90°

d.

80°

Discuss
Answer: (c).90°
Q14.
Experimentation is most desirable over computational methods by every means.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q15.
Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______

a.

single gene in at least one genome

b.

multiple genes in at least one genome

c.

multiple genes in various genomes

d.

single gene in various genomes

Discuss
Answer: (a).single gene in at least one genome
Q16.
Which of the following is untrue about Amino acid conservation?

a.

It has been known for some time that conservation of residues at the surface of a protein family is often related to function

b.

Conservation of residues at the core of a protein family is often related to function

c.

This may be an enzyme active-site or binding site

d.

Unlike hydrophobicity or electrostatic potential, displaying residue conservation on the molecular surface has no physical or chemical basis

Discuss
Answer: (b).Conservation of residues at the core of a protein family is often related to function
Q17.
Which of the following is untrue about Shape Complementarity?

a.

The complementarity between two proteins or a protein and ligand can be described by surface contact or overlap

b.

The complementarity between two proteins or a protein and ligand can be described by the overall buried surface area of two molecules in contact

c.

The complementarity between two proteins or a protein and ligand can be described by the number of adjacent surface points (atoms or residues)

d.

The hydrophobic effect barely has impact on protein folding

Discuss
Answer: (d).The hydrophobic effect barely has impact on protein folding
Q18.
The burial of surface area (or the maximization of surface contact) is an approximation of the effect of shape complementarity.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q19.
Which of the following is untrue about Grid Representation?

a.

To speed up the matching process the topology of the protein can be simplified from atomic level detail to a series of cubic elements

b.

To speed up the matching process discretizing the 3-dimensional space using a grid is done

c.

Discretizing allows very fast computer matching using search methods such as Fourier transform

d.

Fourier transform is hardly used in computer matching

Discuss
Answer: (d).Fourier transform is hardly used in computer matching
Q20.
In Grid representation, in a translational scan the mobile molecule B moves through the grid representing the static molecule A and a signal describing shape complementarity, fc, is generated for each mapping. Mathematically the correlation function, fc, of fA and fB is given by ______ where N is the number of grid points along the cubic axes i, j, and k and ฮฑ, ฮฒ, and ฮณ are the translational vectors of the mobile molecule B relative to the static one A.

a.

fc = \(\sum_{i=1,j=1,k=1}^N\) (fA,i,j,k * fBi+ฮฑj+ฮฒk+ษฃ)

b.

fc = \(\sum_{i=0,j=0,k=0}^N\) (fA,i,j,k * fBi+ฮฑj+ฮฒk+ษฃ)

c.

fc = \(\sum_{i=1,j=1,k=1}^N\) (fA,0,0,0 * fBi+ฮฑj+ฮฒk+ษฃ)

d.

fc = \(\sum_{i=0,j=0,k=0}^N\) (f0,i,j,k * fBi+ฮฑj+ฮฒk+ษฃ)

Discuss
Answer: (a).fc = \(\sum_{i=1,j=1,k=1}^N\) (fA,i,j,k * fBi+ฮฑj+ฮฒk+ษฃ)
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