Protein Biomolecular Interactions MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Protein Biomolecular Interactions, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Protein Biomolecular Interactions MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Protein Biomolecular Interactions mcq questions that explore various aspects of Protein Biomolecular Interactions problems. Each MCQ is crafted to challenge your understanding of Protein Biomolecular Interactions principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Protein Biomolecular Interactions MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Protein Biomolecular Interactions. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

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Protein Biomolecular Interactions MCQs | Page 3 of 7

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Q21.
Genetic methods (genetic algorithms and evolutionary programming) store multiple solutions. These solutions form a population of members.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q22.
Stochastic methods can guarantee reaching a global optimal solution and the methods are computationally costly in comparison to the other methods.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q23.
Which of the following is true regarding Protein flexibility?

a.

Methods have been described for the introduction of side-chain flexibility to both protein-ligand and protein-protein docking

b.

Methods have been described for the introduction of side-chain flexibility to protein-ligand docking only

c.

The Mean Field principle is rarely used in this

d.

Methods have been described for the introduction of side-chain flexibility to protein-protein docking only

Discuss
Answer: (a).Methods have been described for the introduction of side-chain flexibility to both protein-ligand and protein-protein docking
Q24.
In a similar way to structure prediction methods models can be evaluated using RMSD to measure the similarity between two molecular complexes.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q25.
In case of protein-protein docking, the level of success is dependent on the system under study.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q26.
There was little degree of success in docking an antibody-antigen complex in the second challenge for the protein-protein docking evaluation.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q27.
The ______ is an ongoing community-wide experiment on the comparative evaluation of protein-protein docking for structure prediction.

a.

Chronological Assignment of Prediction of Interactions (CAPRI)

b.

Chronological Assessment of Prediction of Interactions (CAPRI)

c.

Critical Assignment of Prediction of Interactions (CAPRI)

d.

Critical Assessment of Prediction of Interactions (CAPRI)

Discuss
Answer: (d).Critical Assessment of Prediction of Interactions (CAPRI)
Q28.
Which of the following is incorrect about Purification of protein complexes followed by mass spectrometry?

a.

Isolating protein complexes from cells allows identification of interactions between ensembles of proteins instead of just pairs

b.

Systematic purification of complexes on a large scale is done by tagging hundreds of genes with an epitope

c.

UnLike in the yeast-two-hybrid assay, this does not involve chimeric genes

d.

Affinity purification based on the epitope will then extract all the proteins attached to the bait protein from cell lysates

Discuss
Answer: (c).UnLike in the yeast-two-hybrid assay, this does not involve chimeric genes
Q29.
Which of the following is untrue?

a.

Many entries in the Protein DataBank (PDB) are three-dimensional structures of multiple domains

b.

The structures in PDB provide experimental information about interactions between domains at atomic detail

c.

There are comparatively few three-dimensional structures compared to the amount of data available from the lower resolution large-scale experiments

d.

Many entries in the Protein DataBank (PDB) are two-dimensional structures of multiple domains

Discuss
Answer: (d).Many entries in the Protein DataBank (PDB) are two-dimensional structures of multiple domains
Q30.
In protein domain family interaction map, the physical contacts of the domains in different families are represented by the lines between the nodes.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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