RNA Structure Prediction MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on RNA Structure Prediction, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our RNA Structure Prediction MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of RNA Structure Prediction mcq questions that explore various aspects of RNA Structure Prediction problems. Each MCQ is crafted to challenge your understanding of RNA Structure Prediction principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our RNA Structure Prediction MCQs are your pathway to success in mastering this essential Bioinformatics topic.

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RNA Structure Prediction MCQs | Page 6 of 9

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Q51.
Which of the following is incorrect about the RNA structure prediction?

a.

Given the sequence, it provides an ab initio prediction of secondary structure

b.

From the many possible choices of complementary sequences that can potentially base-pair, the compatible sets that provide the highest energy molecules are chosen

c.

Structures with energies almost as stable as the most stable one may also be produced

d.

Regions whose predictions are the most reliable can be identified from such an analysis

Discuss
Answer: (b).From the many possible choices of complementary sequences that can potentially base-pair, the compatible sets that provide the highest energy molecules are chosen
Q52.
A type of RNA secondary structure prediction method takes into account conserved patterns of base-pairing that are conserved during evolution of a given class of RNA molecules.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q53.
RNA secondary structure is composed primarily of triple-stranded RNA regions formed by folding the single-stranded molecule back twice on itself.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q54.
____ wobble pairs may be produced in these double-stranded regions.

a.

A/A

b.

A/U

c.

G/C

d.

G/U

Discuss
Answer: (d).G/U
Q55.
In predicting RNA secondary structure, some simplifying assumptions are usually made, like the _____ structure is similar to the _____

a.

most likely, energetically most unstable structure

b.

most unlikely, energetically most stable structure

c.

most likely, energetically most stable structure

d.

least likely, energetically most stable structure

Discuss
Answer: (c).most likely, energetically most stable structure
Q56.
The Second assumption in predicting RNA secondary structure is that the energy associated with any position in the structure is _____ influenced by local sequence and structure.

a.

only

b.

not at all

c.

partially

d.

never

Discuss
Answer: (a).only
Q57.
The third assumption in predicting RNA secondary structure is that the structure is assumed to be formed by _____ of the chain back on itself in a manner that ________

a.

crossing, produces knots

b.

crossing, does not produce any knots

c.

folding, produces knots

d.

folding, does not produce any knots

Discuss
Answer: (d).folding, does not produce any knots
Q58.
Martinez (1984) made a list of possible double-stranded regions, and these regions were then given weights in proportion to their equilibrium constants, calculated by ______

a.

the Boltzmann function [exp (-∆G/RT²)]

b.

the Boltzmann function [exp (-∆G/RT)]

c.

the Boltzmann function [exp (-∆G/RT -T)]

d.

the Boltzmann function [exp (∆G/RT)]

Discuss
Answer: (b).the Boltzmann function [exp (-∆G/RT)]
Q59.
In 1971, first estimation of the energy associated with regions of secondary structure by extrapolation from studies with small molecules was done and then an attempt was made to predict which configurations of larger molecules were the most energetically stable.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q60.
Nussinov and Jacobson (1980) were the first to design a precise and efficient algorithm for predicting secondary structure.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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