RNA Structure Prediction MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on RNA Structure Prediction, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our RNA Structure Prediction MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of RNA Structure Prediction mcq questions that explore various aspects of RNA Structure Prediction problems. Each MCQ is crafted to challenge your understanding of RNA Structure Prediction principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our RNA Structure Prediction MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of RNA Structure Prediction. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your RNA Structure Prediction knowledge to the test? Let's get started with our carefully curated MCQs!

RNA Structure Prediction MCQs | Page 8 of 9

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Q71.
Originally, the FOLD program of _____ predicted _____ having the minimum free energy.

a.

M. Zuker, two structures

b.

M. Wunsch, two structures

c.

M. Zuker, only one

d.

M. Wunsch, only one

Discuss
Answer: (c).M. Zuker, only one
Q72.
To find suboptimal structures, the dynamic programming method was modified.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q73.
In the programs related to FOLD, the second region, the ________ region, is used to calculate the energy of the ________ structure.

a.

included, most likely

b.

included, best

c.

excluded, least likely

d.

excluded, best

Discuss
Answer: (d).excluded, best
Q74.
In the programs related to FOLD, All complementary base pairs can be sampled in a fashion to determine which are present in a suboptimal structure.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q75.
The program may be instructed to find structures within a certain percentage of the minimum free energy.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q76.
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Pnum?

a.

is the total number of energy dots regardless of color in the i th row and i th column of the energy dot plot

b.

is the total number of energy dots considering the color in the ith row and ith column of the energy dot plot

c.

represents in an unfiltered dot plot

d.

represents the number of base pairs

Discuss
Answer: (b).is the total number of energy dots considering the color in the ith row and ith column of the energy dot plot
Q77.
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Hnum?

a.

is the sum of Pnum(i) and Pnum(j) -1

b.

is the sum of Pnum(i) and Pnum(j) + 1

c.

is the total number of dots in the ith row and jth column

d.

represents the total number of base pairs with the ith or jth base in the predicted structures

Discuss
Answer: (b).is the sum of Pnum(i) and Pnum(j) + 1
Q78.
Three scores, Pnum (i), Hnum (i,j), and Ssum, have been derived to assist with a determination of the reliability of a secondary structure prediction for a particular base i or a base pair i,j. Which of the following is not a correct regarding Ssum?

a.

is also called as ss-count

b.

is the number of foldings in which base i is single-stranded divided by m, the number of folding

c.

is the number of foldings in which base i is single-stranded multiplied by m, the number of folding

d.

gives the probability that base i is single-stranded

Discuss
Answer: (c).is the number of foldings in which base i is single-stranded multiplied by m, the number of folding
Q79.
A limitation of the Zuker method and other methods (Nakaya et al. 1995) for computing suboptimal RNA structures is that they do not compute all the structures within a given energy range of the minimum free-energy structure.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q80.
These limitations of the Zuker method and other methods have been largely overcome by using an algorithm originally described by Waterman and Byers (1985) for finding sequence alignments within a certain range of the optimal one by modifications of the trace-back procedure used in dynamic programming.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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