Multiple Sequence Alignment MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Multiple Sequence Alignment, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Multiple Sequence Alignment MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Multiple Sequence Alignment mcq questions that explore various aspects of Multiple Sequence Alignment problems. Each MCQ is crafted to challenge your understanding of Multiple Sequence Alignment principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Multiple Sequence Alignment MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Multiple Sequence Alignment. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Multiple Sequence Alignment knowledge to the test? Let's get started with our carefully curated MCQs!

Multiple Sequence Alignment MCQs | Page 6 of 8

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Q51.
Which of the following is not among the methods for finding localized sequence similarity?

a.

Profile Analysis

b.

Block Analysis

c.

Extraction of Blocks from a Global or Local MSA

d.

Pattern blocking

Discuss
Answer: (d).Pattern blocking
Q52.
Profiles are found by performing the _____ MSA of a group of sequences and then removing the _______ regions in the alignment into a smaller MSA.

a.

local, more highly conserved

b.

global, low conserved

c.

global, more highly conserved

d.

local, low conserved

Discuss
Answer: (c).global, more highly conserved
Q53.
The program Profilemake can be used to produce a profile from an MSA.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q54.
Which of the following is untrue regarding the block analysis method?

a.

Blocks represent a conserved region in the MSA

b.

Blocks differ from profiles in lacking insert and delete positions in the sequences

c.

Every column includes only matches and mismatches

d.

Blocks may be made by searching for a section of an MSA alignment that is low conserved

Discuss
Answer: (d).Blocks may be made by searching for a section of an MSA alignment that is low conserved
Q55.
Block analysis methods use substitution matrices such as the PAM and BLOSUM matrices to score matches.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q56.
In the method of extraction of blocks from a global or local MSA, a global MSA of related protein sequences usually includes regions that have been aligned without gaps in any of the sequences.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q57.
Which of the following is not true regarding the BLOCKS?

a.

Blocks of width 10–55 are extracted from a protein MSA

b.

The protein MSA is up to 400 sequences

c.

The program doesn’t accept manually reformatted MSAs

d.

The program accepts FASTA format

Discuss
Answer: (c).The program doesn’t accept manually reformatted MSAs
Q58.
The pattern searching method type of analysis was performed on groups of related proteins, and the amino acid patterns that were located may be found in the Prosite catalog.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q59.
Although MOTIF program is used successfully for making the BLOCKS database, it is limited in the pattern sizes that can be found.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q60.
Which of the following is not true regarding the BLOCKS?

a.

The BLOCKS server can extract a conserved, ungapped region from a MSA to produce a sequence block

b.

The server can also find blocks in a set of unaligned, input sequences and maintains a large database of blocks based on an analysis of proteins in the Prosite catalog

c.

Blocks are found by the Protomat program

d.

The program MOTIF doesn’t locate spaced patterns

Discuss
Answer: (d).The program MOTIF doesn’t locate spaced patterns
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