Multiple Sequence Alignment MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Multiple Sequence Alignment, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Multiple Sequence Alignment MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Multiple Sequence Alignment mcq questions that explore various aspects of Multiple Sequence Alignment problems. Each MCQ is crafted to challenge your understanding of Multiple Sequence Alignment principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Multiple Sequence Alignment MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Multiple Sequence Alignment. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Multiple Sequence Alignment knowledge to the test? Let's get started with our carefully curated MCQs!

Multiple Sequence Alignment MCQs | Page 8 of 8

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Q71.
Analysis of MSAs for conserved blocks of sequence leads to production of the position-specific scoring matrix.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q72.
The quality and quantity of information provided by the PSSM also varies for ________ in the motif.

a.

each row

b.

each column

c.

rows and columns

d.

neither the rows nor the columns

Discuss
Answer: (b).each column
Q73.
Two considerations arise in trying to tune the PSSM so that it adequately represents the training sequences. Which of the following is not their description?

a.

If a given column in 20 sequences has only isoleucine, it is not very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function

b.

If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function

c.

If the number of sequences with the found motif is large and reasonably diverse, the sequences represent a good statistical sampling of all sequences that are ever likely to be found with that same motif

d.

Another column in the motif from the 20 sequences may have several amino acids, and some amino acids may not be represented at all

Discuss
Answer: (b).If a given column in 20 sequences has only isoleucine, it is very likely that different amino acid will be found in other sequences with that motif because the residue is probably important for function
Q74.
If a good sampling of sequences is _______ the number of sequences is _________ and the motif structure is ________ it should, in principle, be possible to obtain frequencies highly representative of the same motif in other sequences also.

a.

available, sufficiently large, not too complex

b.

unavailable, sufficiently large, not too complex

c.

unavailable, sufficiently small, not too complex

d.

available, sufficiently large, too complex

Discuss
Answer: (a).available, sufficiently large, not too complex
Q75.
If the data set is _______ then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif.

a.

small, distinct

b.

small, almost identical

c.

large, almost identical

d.

large, distinct

Discuss
Answer: (b).small, almost identical
Q76.
Even if many pseudocounts are added in comparison to real sequence counts, the amino acid frequencies will not have any effect or influence.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q77.
Which of the following is not a feature of editors and formatters?

a.

provision for displaying the sequence on a color monitor with residue colors to aid in a clear visual representation of the alignment

b.

recognition of the multiple sequence format that was output by the MSA (Multiple Sequence Alignment) program

c.

maintenance of the alignment in a suitable format when the editing is completed

d.

disallowing shading conserved residues in the alignment

Discuss
Answer: (d).disallowing shading conserved residues in the alignment
Q78.
GDE (Genetic Data Environment) provides a general interface on UNIX machines for sequence analysis, sequence alignment editing, and display.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q79.
MACAW is a local multiple sequence alignment program only.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q80.
Two commonly encountered examples are the Genetics Computer Group’s MSF format and the CLUSTALW ALN format.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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