Phylogenetic Methods and Programs MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Phylogenetic Methods and Programs, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Phylogenetic Methods and Programs MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Phylogenetic Methods and Programs mcq questions that explore various aspects of Phylogenetic Methods and Programs problems. Each MCQ is crafted to challenge your understanding of Phylogenetic Methods and Programs principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Phylogenetic Methods and Programs MCQs are your pathway to success in mastering this essential Bioinformatics topic.

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Q31.
Which of the following is untrue about distance based methods?

a.

The computed evolutionary distances can be used to construct a matrix of distances between all individual pairs of taxa

b.

Clustering is the only method among the algorithms for the distance-based tree-building method

c.

The clustering-type algorithms compute a tree based on a distance matrix starting from the most similar sequence pairs

d.

Based on the pairwise distance scores in the matrix, a phylogenetic tree can be constructed for all the taxa involved

Discuss
Answer: (b).Clustering is the only method among the algorithms for the distance-based tree-building method
Q32.
Which of the following is untrue about the Unweighted Pair Group Method Using Arithmetic Average?

a.

The simplest clustering method is UPGMA, which builds a tree by a sequential clustering method

b.

Given a distance matrix, it starts by grouping two taxa with the largest pairwise distance in the distance matrix

c.

The distances between this new composite taxon and all remaining taxa are calculated to create a reduced matrix

d.

The grouping process is repeated and another newly reduced matrix is created

Discuss
Answer: (b).Given a distance matrix, it starts by grouping two taxa with the largest pairwise distance in the distance matrix
Q33.
The basic assumption of the UPGMA method is that all taxa evolve at a constant rate and that they are equally distant from the root, implying that a molecular clock is in effect.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q34.
In the Neighbor Joining step, The UPGMA method uses unweighted distances and assumes that all taxa have constant evolutionary rates.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q35.
Corrects for unequal evolutionary rates between sequences by using a conversion step. This conversion requires the calculations of β€œr-values” and β€œtransformed r-values” using the following formula ______

a.

dᴀʙ’ = dα΄€Κ™ βˆ’ 1/4 × (rα΄€ + rΚ™)

b.

dᴀʙ’ = dα΄€Κ™ βˆ’ 1/2 × (rα΄€ + rΚ™)

c.

dᴀʙ’ = dα΄€Κ™ βˆ’ 1/3 × (rα΄€ + rΚ™)

d.

dᴀʙ’ = (dα΄€Κ™/3) βˆ’ 1/2 × (rα΄€ + rΚ™)

Discuss
Answer: (b).dᴀʙ’ = dα΄€Κ™ βˆ’ 1/2 × (rα΄€ + rΚ™)
Q36.
A generalized expression of the r-value is ri calculated based on the following formula _______

a.

ri = βˆ‘dij + dj²

b.

ri = βˆ‘dij

c.

ri = βˆ‘dij + di

d.

ri = βˆ‘dij + dj

Discuss
Answer: (b).ri = βˆ‘dij
Q37.
The tree construction process is somewhat similar to that used UPGMA.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q38.
Which of the following is untrue about the Optimality-Based Methods?

a.

The clustering-based methods produce multiple trees as output

b.

Optimality-based methods select a tree that best fits the actual evolutionary distance matrix

c.

There is no criterion in judging how this tree is compared to other alternative trees

d.

Optimality-based methods have a well-defined algorithm to compare all possible tree topologies

Discuss
Answer: (a).The clustering-based methods produce multiple trees as output
Q39.
Which of the following is untrue about the Fitch–Margoliash?

a.

Method selects a best tree among all possible trees based on minimal deviation between the distances calculated in the overall branches in the tree and the distances in the original dataset

b.

It starts by randomly clustering two taxa in a node

c.

It starts by creating three equations to describe the distances

d.

The method searches for some specific tree topologies

Discuss
Answer: (d).The method searches for some specific tree topologies
Q40.
Minimum evolution (ME) constructs a tree with a similar procedure, but uses a different optimality criterion that finds a tree among all possible trees with a minimum overall branch length. The optimality criterion relies on the formula S = βˆ‘bi where bi is the (i)th branch length.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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