Phylogenetic Methods and Programs MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Phylogenetic Methods and Programs, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Phylogenetic Methods and Programs MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Phylogenetic Methods and Programs mcq questions that explore various aspects of Phylogenetic Methods and Programs problems. Each MCQ is crafted to challenge your understanding of Phylogenetic Methods and Programs principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Phylogenetic Methods and Programs MCQs are your pathway to success in mastering this essential Bioinformatics topic.

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Q71.
Which of the following is untrue regarding the maximum parsimony method?

a.

This method predicts the evolutionary tree

b.

It minimizes the number of steps required to generate the observed variation in the sequences

c.

The method is also sometimes referred to as the minimum evolution method

d.

Only a pairwise sequence alignment is required to predict which sequence positions are likely to correspond

Discuss
Answer: (d).Only a pairwise sequence alignment is required to predict which sequence positions are likely to correspond
Q72.
Which of the following is untrue regarding the maximum parsimony method?

a.

The analysis steps are continued for every position in the sequence alignment

b.

This method is used for large numbers of sequences

c.

Those trees that produce the smallest number of changes overall for all sequence positions are identified

d.

This method is used for sequences that are quite similar

Discuss
Answer: (b).This method is used for large numbers of sequences
Q73.
Which of the following is untrue regarding the programs for analysis of nucleic acid sequences?

a.

DNAPARS treats gaps as a fifth nucleotide state

b.

DNAPENNY performs parsimonious phylogenies by branch-and-bound search

c.

DNAPENNY can analyze sequences up to 11 or 12

d.

Compatibility criterion is not involved in DNACOMP

Discuss
Answer: (d).Compatibility criterion is not involved in DNACOMP
Q74.
PROTPARS counts the minimum number of mutations to change a codon for the first amino acid into a codon for the second amino acid, but only scores those mutations in the mutational path that actually change the amino acid.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q75.
Parsimony can give ________ information when rates of sequence change _______ in the different branches of a tree that are represented by the sequence data.

a.

misleading, vary

b.

useful, change

c.

misleading, are constant

d.

sometimes contradicting, are constant

Discuss
Answer: (a).misleading, vary
Q76.
Which of the following is untrue regarding the distance methods?

a.

The sequence pairs that have the largest number of sequence changes between them are termed ‘neighbors’

b.

On a tree, these sequences share a node or common ancestor position and are each joined to that node by a branch

c.

It produces a phylogenetic tree of the group

d.

It employs the number of changes between each pair in a group of sequences

Discuss
Answer: (a).The sequence pairs that have the largest number of sequence changes between them are termed ‘neighbors’
Q77.
Which of the following is untrue regarding the distance methods?

a.

The distance method was pioneered by Feng and Doolittle

b.

A collection of programs by authors Feng and Doolittle will produce both an alignment and tree of a set of protein sequences

c.

The program CLUSTALW uses the neighbor-joining distance method as a guide to multiple sequence alignments

d.

Among the Programs of the PHYLIP package, DNADIST is not one of them

Discuss
Answer: (d).Among the Programs of the PHYLIP package, DNADIST is not one of them
Q78.
Which of the following is untrue regarding the Distance analysis programs in PHYLIP?

a.

FITCH estimates a phylogenetic tree assuming additivity of branch lengths

b.

FITCH uses the Fitch-Margoliash method

c.

FITCH assumes a molecular clock but KITSCH does not

d.

NEIGHBOR estimates phylogenies using the neighbor-joining or unweighted pair group method with arithmetic mean (UPGMA)

Discuss
Answer: (c).FITCH assumes a molecular clock but KITSCH does not
Q79.
Which of the following is untrue regarding the neighbor-joining method?

a.

It is very much like the Fitch-Margoliash method

b.

It is totally dissimilar than the Fitch-Margoliash method

c.

It is especially suitable when the rate of evolution of the separate lineages under consideration varies

d.

When the branch lengths of trees of known topology are allowed to vary in a manner that simulates varying levels of evolutionary change, it is the most reliable method

Discuss
Answer: (b).It is totally dissimilar than the Fitch-Margoliash method
Q80.
Neighbor-joining chooses the sequences that should be joined to give the best least squares estimates of the branch lengths that most closely reflect the actual distances between the sequences.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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