Phylogenetic Methods and Programs MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Phylogenetic Methods and Programs, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Phylogenetic Methods and Programs MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Phylogenetic Methods and Programs mcq questions that explore various aspects of Phylogenetic Methods and Programs problems. Each MCQ is crafted to challenge your understanding of Phylogenetic Methods and Programs principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Phylogenetic Methods and Programs MCQs are your pathway to success in mastering this essential Bioinformatics topic.

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Q81.
Which of the following is wrong statement about the maximum likelihood approach?

a.

This method doesn’t always involve probability calculations

b.

It finds a tree that best accounts for the variation in a set of sequences

c.

The method is similar to the maximum parsimony method

d.

The analysis is performed on each column of a multiple sequence alignment

Discuss
Answer: (a).This method doesn’t always involve probability calculations
Q82.
In about the maximum likelihood approach, for each tree, the number of sequence changes or mutations that may have occurred to give the sequence variation is considered.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q83.
The maximum likelihood method can be used to explore relationships among more diverse sequences, conditions that are not well handled by maximum parsimony methods.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q84.
The main disadvantage of maximum likelihood methods is that they are _____

a.

mathematically less folded

b.

mathematically less complex

c.

computationally lucid

d.

computationally intense

Discuss
Answer: (d).computationally intense
Q85.
Maximum likelihood has also been used for an analysis of mutations in overlapping reading frames in viruses.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q86.
Which of the following is wrong statement about DNAML and DNAMLK?

a.

PHYLIP includes mentioned two programs for this maximum likelihood analysis

b.

DNAML estimates phylogenies from nucleotide sequences by the maximum likelihood method

c.

DNAMLK estimates phylogenies in the same manner as DNAML

d.

DNAMLK estimates phylogenies without molecular clock

Discuss
Answer: (d).DNAMLK estimates phylogenies without molecular clock
Q87.
Which of the following is wrong statement about the maximum likelihood method’s steps?

a.

It starts with an evolutionary model of sequence change that provides estimates of rates of substitution of one base for another

b.

In the beginning there is an evolutionary model of sequence change that provides estimates of transitions and transversions in a set of nucleic acid sequences

c.

The rates of all possible substitutions are chosen so that the base composition differs

d.

The set of sequences is then aligned

Discuss
Answer: (c).The rates of all possible substitutions are chosen so that the base composition differs
Q88.
Once all positions in the sequence alignment have been examined, the likelihoods given by each column in the alignment for each tree are _____ to give the likelihood of the tree.

a.

multiplied

b.

added

c.

divided

d.

squared

Discuss
Answer: (a).multiplied
Q89.
A method of sequence alignment based on a Model (Bishop and Thompson 1986) was introduced that predicts the manner in which DNA sequences change during evolution. Which of the following is wrong about it?

a.

The basis of this method is to devise a scheme for introducing substitutions, insertions, and gaps into sequences

b.

The basis of this method is to provide a probability that each of these changes occurs over certain periods of evolutionary time

c.

Given each of these predicted changes, the method examines all the possible combinations of mutations to change one sequence into another

d.

Multiple combinations are selected that will be the most likely over time

Discuss
Answer: (d).Multiple combinations are selected that will be the most likely over time
Q90.
A method of sequence alignment based on a Model (Bishop and Thompson 1986) was introduced that predicts the manner in which DNA sequences change during evolution. Which of the following is wrong about it?

a.

This method is different from the Smith-Waterman local alignment algorithm

b.

This method is quite similar to the Smith-Waterman local alignment algorithm

c.

The underlying mutational theory is like those used to produce the PAM matrices for predicting changes in DNA and protein sequences

d.

Sequences are predicted to change by a Markov process such that each mutation in the sequence is independent of previous mutations at that site or at other sites

Discuss
Answer: (b).This method is quite similar to the Smith-Waterman local alignment algorithm
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