Sequence Alignment MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Sequence Alignment, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Sequence Alignment MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Sequence Alignment mcq questions that explore various aspects of Sequence Alignment problems. Each MCQ is crafted to challenge your understanding of Sequence Alignment principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Sequence Alignment MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Sequence Alignment. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Sequence Alignment knowledge to the test? Let's get started with our carefully curated MCQs!

Sequence Alignment MCQs | Page 9 of 15

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Q81.
Use of the dynamic programming method requires a scoring system for the comparison of symbol pairs, and a scheme for GAP penalties.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q82.
After the derivation, the outputs of the dynamic programming are the ratios are called even scores.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q83.
The matrices PAM250 and BLOSUM62 contain _______

a.

positive and negative values

b.

positive values only

c.

negative values only

d.

neither positive nor negative values, just the percentage

Discuss
Answer: (a).positive and negative values
Q84.
The higher is the score in the alignment _________

a.

the more significant is the alignment

b.

or the less it resembles alignments in related proteins

c.

the less significant is the alignment

d.

the less it aligns with the related protein sequence

Discuss
Answer: (a).the more significant is the alignment
Q85.
Gaps are added to the alignment because it ______

a.

increases the matching of identical amino acids at subsequent portions in the alignment

b.

increases the matching of or dissimilar amino acids at subsequent portions in the alignment

c.

reduces the overall score

d.

enhances the area of the sequences

Discuss
Answer: (a).increases the matching of identical amino acids at subsequent portions in the alignment
Q86.
Which of the following is not a description of dynamic programming algorithm?

a.

A method of sequence alignment

b.

A method that can take gaps into account

c.

A method that requires a manageable number of comparisons

d.

This method doesn’t provide an optimal (highest scoring) alignment

Discuss
Answer: (d).This method doesn’t provide an optimal (highest scoring) alignment
Q87.
Which of the following is not a site on internet for alignment of sequence pairs?

a.

BLASTX

b.

BLASTN

c.

SIM

d.

BCM Search Launcher

Discuss
Answer: (a).BLASTX
Q88.
Dayhoff PAM matrices, are based on an evolutionary model of protein change, whereas, BLOSUM matrices, are designed to identify members of the same family.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q89.
A feature of the dynamic programming algorithm is that the alignments obtained depend on the choice of a scoring system for comparing character pairs and penalty scores for gaps.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q90.
Which of the following is untrue regarding dynamic programming algorithm?

a.

The method compares every pair of characters in the two sequences and generates an alignment

b.

The output alignment will include matched and mismatched characters and gaps in the two sequences that are positioned so that the number of matches between identical or related characters is the maximum possible

c.

The dynamic programming algorithm provides a reliable computational method for aligning DNA and protein sequences

d.

This doesn’t allow making evolutionary predictions on the basis of sequence alignments

Discuss
Answer: (d).This doesn’t allow making evolutionary predictions on the basis of sequence alignments
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