Sequence Alignment MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Sequence Alignment, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Sequence Alignment MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Sequence Alignment mcq questions that explore various aspects of Sequence Alignment problems. Each MCQ is crafted to challenge your understanding of Sequence Alignment principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Sequence Alignment MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Sequence Alignment. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Sequence Alignment knowledge to the test? Let's get started with our carefully curated MCQs!

Sequence Alignment MCQs | Page 15 of 15

Discover more Topics under Bioinformatics

Q141.
The truly statistically significant sequence alignment will be able to provide evidence of homology between the sequences involved.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q142.
By calculating alignment scores of a large number of ______ sequence pairs, a distribution model of the ______ sequence scores can be derived.

a.

related, randomized

b.

unrelated, randomized

c.

unrelated, unrandomized

d.

related, unrandomized

Discuss
Answer: (b).unrelated, randomized
Q143.
Many studies have demonstrated that the distribution of similarity scores assumes a peculiar shape that resembles a highly skewed normal distribution with a long tail on one side. The distribution matches the _______

a.

Gumble elective value distribution

b.

Gumble extreme void distribution

c.

Gumble end value distribution

d.

Gumble extreme value distribution

Discuss
Answer: (d).Gumble extreme value distribution
Q144.
Which of the following is a part of the statistical test of sequences?

a.

An optimal alignment between two chosen sequences is obtained at the end

b.

Unrelated sequences of the same length are then generated through a randomization process

c.

Unrelated sequences of the different length are then generated through a randomization process

d.

Related sequences of the same length are then generated through a randomization process

Discuss
Answer: (b).Unrelated sequences of the same length are then generated through a randomization process
Q145.
In the statistical test, randomization process in which one of the two given sequences is randomly shuffled.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q146.
What is used to generate parameters for the extreme distribution?

a.

The pool of alignment scores from the shuffled sequences

b.

A single score of a shuffled sequence

c.

The pool of alignment scores from the unshuffled sequences

d.

The basic optimal score computed at the beginning of the test

Discuss
Answer: (a).The pool of alignment scores from the shuffled sequences
Q147.
If the score is located in the extreme margin of the distribution, that means that the alignment between the two sequences is ______ due to random chance and is thus considered ______

a.

unlikely, significant

b.

unlikely, insignificant

c.

unlikely, insignificant

d.

very likely, significant

Discuss
Answer: (a).unlikely, significant
Q148.
It is not known whether the Gumble distribution applies equally well to gapped alignments.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q149.
Which of the following is untrue about the PRSS program?

a.

It stands for Probability of Random Shuffles

b.

It is a web-based program that can be used to evaluate the statistical significance of DNA or protein sequence alignment

c.

It first aligns two sequences using the Needleman-Wunsch algorithm and calculates the score

d.

It holds one sequence in its original form and randomizes the order of residues in the other sequence.

Discuss
Answer: (c).It first aligns two sequences using the Needleman-Wunsch algorithm and calculates the score
Q150.
The major disadvantage of the PRSS program is that it doesn’t allow partial shuffling.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Page 15 of 15