DNA and Genomic Sequencing MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on DNA and Genomic Sequencing, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our DNA and Genomic Sequencing MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of DNA and Genomic Sequencing mcq questions that explore various aspects of DNA and Genomic Sequencing problems. Each MCQ is crafted to challenge your understanding of DNA and Genomic Sequencing principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our DNA and Genomic Sequencing MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of DNA and Genomic Sequencing. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

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DNA and Genomic Sequencing MCQs | Page 10 of 17

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Q91.
Gene identification in prokaryotic organisms is simplified by their lacking _________

a.

exons

b.

introns

c.

coding segments

d.

useful nucleotide sequences

Discuss
Answer: (b).introns
Q92.
Which of the given statement is incorrect?

a.

The predicted set of proteins for the genome is referred to as the proteome

b.

The amino acid sequence of proteins encoded by the predicted genes is used as a query of the protein sequence databases in a database similarity search

c.

A match of a predicted protein sequence to one or more database sequences serves only to identify the gene function but it doesn’t validate the gene prediction

d.

The genome sequence is annotated with the information on gene content and predicted structure, gene location, and functional predictions

Discuss
Answer: (c).A match of a predicted protein sequence to one or more database sequences serves only to identify the gene function but it doesn’t validate the gene prediction
Q93.
Which of the following information is not directly obtained by microarray analysis?

a.

Which genes are expressed at a particular stage of the cell cycle

b.

Which genes are expressed at a particular stage of developmental cycle of an organism

c.

Which genes are depleted at what time

d.

Genes that respond to a given environmental signal to the same extent

Discuss
Answer: (c).Which genes are depleted at what time
Q94.
Which of the given statement is incorrect about Functional Genomics?

a.

Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene

b.

An abnormal properties of the mutant organism does not reveal the gene function

c.

When two or more members of a gene family are found, rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family

d.

A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection

Discuss
Answer: (b).An abnormal properties of the mutant organism does not reveal the gene function
Q95.
Which of the given statement is incorrect about the gene map?

a.

Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by reassembly of fragments in a different order can produce new gene maps

b.

Gene order is only revealed by the physical order of genes on the chromosome

c.

Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next

d.

These types of evolutionary changes in genomes have been modeled by computational methods

Discuss
Answer: (b).Gene order is only revealed by the physical order of genes on the chromosome
Q96.
In the program COGNITOR each protein in the proteome is used as a query of a database of protein clusters.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q97.
WU-BLAST produces P scores and BLAST (NCBI) produces E scores where _________

a.

E = ln (1 + P²)

b.

E = ln (1 – P²)

c.

E = ln (1 + P)

d.

E = ln (1 – P)

Discuss
Answer: (d).E = ln (1 – P)
Q98.
In Proteolysis and fragment sequencing, Protein spots may be excised from a two-dimensional protein gel and subjected to a combination of amino acid sequencing and cleavage analyses using the techniques of mass spectrometry and high-pressure liquid chromatography.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q99.
In Protein 2D gel Electrophoresis, Individual proteins produced by the genome can be separated to _____ by this method and specific ones identified by various _______

a.

smaller extent, biochemical and immunological tests

b.

a large extent, biochemical and immunological tests

c.

a large extent, biochemical tests only

d.

smaller extent, purely mechanical tests

Discuss
Answer: (b).a large extent, biochemical and immunological tests
Q100.
In Metabolic pathways and regulation, as genes are identified in a new genome sequence, some will be found that are known to act sequentially in a metabolic pathway or to have a known role in gene regulation in other organisms.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
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