DNA and Genomic Sequencing MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on DNA and Genomic Sequencing, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our DNA and Genomic Sequencing MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of DNA and Genomic Sequencing mcq questions that explore various aspects of DNA and Genomic Sequencing problems. Each MCQ is crafted to challenge your understanding of DNA and Genomic Sequencing principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our DNA and Genomic Sequencing MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of DNA and Genomic Sequencing. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your DNA and Genomic Sequencing knowledge to the test? Let's get started with our carefully curated MCQs!

DNA and Genomic Sequencing MCQs | Page 12 of 17

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Q111.
In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.

a.

PubChem

b.

Genbank

c.

MeSH

d.

SwissProt

Discuss
Answer: (d).SwissProt
Q112.
In all-against-all self comparison, A comparison is made in which every protein is used as a query in a similarity search against a database composed of the rest of the proteome, and the significant matches are identified by a low expect value.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q113.
Processed pseudogenes are also derived from a functional gene and they contain introns and a promoter.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q114.
Pseudogenes are DNA sequences that were derived from distinct genes but which have acquired mutations that are deleterious to function in the same period of time.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q115.
New gene functions are thought to be gained by duplication of an existing gene creating two tandem copies.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q116.
Comparative genomics includes a comparison of gene number, gene content, and gene location in both prokaryotic and eukaryotic groups of organisms.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q117.
Which of the following information Sequence comparisons do not provide?

a.

Gene relationships

b.

Function history

c.

Evolutionary history

d.

Gene locations

Discuss
Answer: (d).Gene locations
Q118.
Which of the given statements is incorrect?

a.

Proteins may be clustered into families on the basis of either sequence or structural similarity

b.

Proteins often comprise separate domains

c.

The number of protein sequences that are available is insufficient to determine that domain shuffling occurs in evolution

d.

Proteins are modular

Discuss
Answer: (c).The number of protein sequences that are available is insufficient to determine that domain shuffling occurs in evolution
Q119.
Which of the given statements is incorrect?

a.

Two tandem copies of a gene are produced while Proteins with new functions are produced

b.

Proteins with new functions are produced by a gene duplication event

c.

Assortment and reassortment of protein domains takes place in individual genomes

d.

In no case the two duplicated genes both undergo change

Discuss
Answer: (d).In no case the two duplicated genes both undergo change
Q120.
Which of the given statements is incorrect?

a.

The processes of domain assortment and gene duplication produce families of proteins in organisms

b.

Following speciation, a newly derived genome will inherit the families of ancestor organisms, but will also develop new ones to meet evolutionary challenges

c.

Comparison of each of the proteins encoded by an organism with every protein, an all-against-all comparison, reveals which protein families have been amplified and what rearrangements have occurred as steps in the evolutionary process

d.

When two or more proteins in the proteome share a high degree of similarity they are least likely to be paralogs

Discuss
Answer: (d).When two or more proteins in the proteome share a high degree of similarity they are least likely to be paralogs
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