DNA and Genomic Sequencing MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on DNA and Genomic Sequencing, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our DNA and Genomic Sequencing MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of DNA and Genomic Sequencing mcq questions that explore various aspects of DNA and Genomic Sequencing problems. Each MCQ is crafted to challenge your understanding of DNA and Genomic Sequencing principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our DNA and Genomic Sequencing MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of DNA and Genomic Sequencing. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your DNA and Genomic Sequencing knowledge to the test? Let's get started with our carefully curated MCQs!

DNA and Genomic Sequencing MCQs | Page 11 of 17

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Q101.
_______ of the Drosophila sequence is composed of TEs and _____ is heterochromatic regions that do not include genes.

a.

one-fourth, one-third

b.

one-fifth, one-fourth

c.

one-sixth, one-eighth

d.

one-sixth, one-third

Discuss
Answer: (d).one-sixth, one-third
Q102.
Yeast is about ______ compact than E. coli.

a.

fivefold, less

b.

threefold, more

c.

twofold, less

d.

twofold, more

Discuss
Answer: (c).twofold, less
Q103.
The ________ are _______ by genetic structure to retroviruses.

a.

STR retrotransposons, related

b.

LTR retrotransposons, related

c.

STR transposons, related

d.

LTR retrotransposons, not related

Discuss
Answer: (b).LTR retrotransposons, related
Q104.
Which of the given statement is incorrect?

a.

As in an all-by-all protein comparison within a proteome, a matrix of alignment scores with E values is made, and the most closely related sequences in the two organisms are identified

b.

To perform a between-proteome analysis, proteome databases are made for the known and predicted genes of two or more genomes

c.

Each protein of one proteome is selected in turn as a query of the proteome of another organism or the combined proteome of a group of organisms

d.

Each protein of one proteome is selected in turn as a query of the proteome of another single organism only

Discuss
Answer: (d).Each protein of one proteome is selected in turn as a query of the proteome of another single organism only
Q105.
The higher the E value, the more significant the alignment between a pair of matching sequences.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q106.
Which of the given statement is incorrect about proteome analyses?

a.

For BLAST, setting an effective database size appropriate for each search and program is important

b.

Due to the large number of comparisons that must be made in these types of analyses and due to the volume of program output, the procedure must be automated on a local machine using Perl scripts or a similar method and a database system

c.

BLAST is used for obtaining a correct statistical evaluation of alignment scores

d.

BLAST does not give statistical evaluation of alignment scores

Discuss
Answer: (d).BLAST does not give statistical evaluation of alignment scores
Q107.
An all-against-all analysis requires first making a database of the proteome. This database is then sequentially searched by each individual protein sequence of the proteome using a rapid database similarity search tool such as _______

a.

XPBLAST

b.

WU-BLAST

c.

BLAST

d.

FASTA

Discuss
Answer: (a).XPBLAST
Q108.
Evolutionary modeling can include various types of analyses. Which is mostly not one of them?

a.

The prediction of chromosomal rearrangements

b.

Eu/Hetero-chromatin structures

c.

Duplications at gene, chromosomal and full genome level

d.

Duplications at the protein domain level

Discuss
Answer: (b).Eu/Hetero-chromatin structures
Q109.
Which of the given statement is incorrect about Clusters of functionally related genes?

a.

In microbial genomes, genes specifying a metabolic pathway may be contiguous on the genome where they are coregulated transcriptionally in an operon by a common promoter

b.

In related organisms, gene order on the chromosome is least likely to be conserved

c.

As the relationship between the organisms decreases, local groups of genes remain clustered together, but chromosomal rearrangements move the clusters to other locations

d.

The function of a particular gene can sometimes be predicted, given the known function of a neighboring, closely linked gene

Discuss
Answer: (b).In related organisms, gene order on the chromosome is least likely to be conserved
Q110.
Which of the given statement is incorrect about Orthologs?

a.

In comparing two proteomes, a common standard is to require that for each pair of orthologs, the first of the pair is the best hit when the second is used to query the proteome of the first

b.

To identify orthologs, each protein in the proteome of an organism is used as a query in a similarity search of a database comprising the proteomes of only one different organism

c.

The best hit in each proteome is likely to be with an ortholog of the query gene

d.

Orthologs are genes that are so highly conserved by sequence in different genomes that the proteins they encode are strongly predicted to have the same structure and function and to have arisen from a common ancestor through speciation

Discuss
Answer: (b).To identify orthologs, each protein in the proteome of an organism is used as a query in a similarity search of a database comprising the proteomes of only one different organism
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