Genomics and Proteomics MCQs

Welcome to our comprehensive collection of Multiple Choice Questions (MCQs) on Genomics and Proteomics, a fundamental topic in the field of Bioinformatics. Whether you're preparing for competitive exams, honing your problem-solving skills, or simply looking to enhance your abilities in this field, our Genomics and Proteomics MCQs are designed to help you grasp the core concepts and excel in solving problems.

In this section, you'll find a wide range of Genomics and Proteomics mcq questions that explore various aspects of Genomics and Proteomics problems. Each MCQ is crafted to challenge your understanding of Genomics and Proteomics principles, enabling you to refine your problem-solving techniques. Whether you're a student aiming to ace Bioinformatics tests, a job seeker preparing for interviews, or someone simply interested in sharpening their skills, our Genomics and Proteomics MCQs are your pathway to success in mastering this essential Bioinformatics topic.

Note: Each of the following question comes with multiple answer choices. Select the most appropriate option and test your understanding of Genomics and Proteomics. You can click on an option to test your knowledge before viewing the solution for a MCQ. Happy learning!

So, are you ready to put your Genomics and Proteomics knowledge to the test? Let's get started with our carefully curated MCQs!

Genomics and Proteomics MCQs | Page 8 of 12

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Q71.
Which of the following is untrue about SAGE?

a.

This approach is much more efficient than the EST analysis

b.

This approach is quite less efficient than the EST analysis

c.

It uses a short nucleotide tag to define a gene transcript

d.

It allows sequencing of multiple tags in a single clone

Discuss
Answer: (b).This approach is quite less efficient than the EST analysis
Q72.
Which of the following is untrue about SAGE?

a.

Sequencing is the most costly and time-consuming step

b.

Here, sequencing is economical but time-consuming step

c.

Sequencing is economical but time-reducing step

d.

It is difficult to know how many tags need to be sequenced to get a good coverage of the entire transcriptome

Discuss
Answer: (a).Sequencing is the most costly and time-consuming step
Q73.
Which of the following is untrue about the drawbacks of SAGE?

a.

One or two sequencing errors in the tag sequence can lead to ambiguous or erroneous tag identification

b.

Correctly sequenced SAGE tag sometimes may correspond to several genes or no gene at all

c.

Correctly sequenced SAGE tag always corresponds to several genes

d.

The drawback with this approach is the sensitivity to sequencing errors

Discuss
Answer: (c).Correctly sequenced SAGE tag always corresponds to several genes
Q74.
SAGEmap is a SAGE database created by NCBI.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q75.
SAGExProfiler doesn’t provide information about overexpressed or silenced genes.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q76.
Which of the following is untrue about SAGE Genie?

a.

It is an NCBI web-based program

b.

It allows matching of experimentally obtained SAGE tags to known genes

c.

It provides an interface for visualizing human gene expression

d.

It doesn’t filter out linker sequences from experimentally obtained SAGE tags

Discuss
Answer: (d).It doesn’t filter out linker sequences from experimentally obtained SAGE tags
Q77.
Which of the following is an incorrect statement?

a.

SAGE and DNA microarrays are both high throughput techniques that determine global mRNA expression levels

b.

Studies have indicated that the gene expression measurements from these methods are highly inconsistent with each other

c.

SAGE does not require prior knowledge of the transcript sequence

d.

DNA microarray experiments can only detect the genes spotted on the microarray

Discuss
Answer: (b).Studies have indicated that the gene expression measurements from these methods are highly inconsistent with each other
Q78.
DNA microarrays measure “absolute” mRNA expression levels without arbitrary reference standards, whereas SAGE indicates the relative expression levels.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (b).False
Q79.
The PCR amplification step involved in the SAGE procedure means that it requires a large quantity of sample mRNA.

a.

True

b.

False

c.

May be True or False

d.

Can't say

Discuss
Answer: (a).True
Q80.
Which of the following is an incorrect statement?

a.

Collecting a SAGE library is very labor intensive and expensive

b.

Collecting a SAGE library is quite economical

c.

SAGE is not suitable for rapid screening of cells

d.

Gene identification from SAGE data is also more cumbersome

Discuss
Answer: (b).Collecting a SAGE library is quite economical
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